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TranscriptomicsTranscriptomic alterations in Trypanosoma cruzi-infected cardiac myocytes
Trypanosoma cruzi infection is a major cause of cardiomyopathy. Gene profiling studies of hearts from infected mice have revealed prominent changes in gene expression within many functional pathways. This variety of transcriptomic changes in infected mice raises the question of whether gene express...
ORGANISM(S): Mus musculus 
2010-05-15 | E-GEOD-17330 | biostudies-arrayexpress
TranscriptomicsTherapy with bone marrow cells recovers gene expression alterations in hearts of mice with chronic chagasic cardiomyopathy
Chronic chagasic cardiomyopathy is one of the leading causes of heart failure in Latin American countries, being associated with intense inflammatory response and fibrosis. We have previously shown that bone marrow mononuclear cell (BMC) transplantation improves inflammation, fibrosis and ventricula...
ORGANISM(S): Mus musculus 
2010-09-17 | E-GEOD-24088 | biostudies-arrayexpress
TranscriptomicsFunctional and Transcriptomic Recovery of Infarcted Mouse Myocardium Treated with Bone Marrow Mononuclear Cells
Although bone marrow-derived mononuclear cells (BMNC) have been extensively used in cell therapy for cardiac diseases, little mechanistic information is available to support reports of their efficacy. To address this shortcoming, we compared structural and functional recovery and associated global g...
ORGANISM(S): Mus musculus 
2011-06-08 | E-GEOD-29769 | biostudies-arrayexpress
TranscriptomicsGene expression changes associated with myocarditis and fibrosis in hearts of mice with chronic chagasic cardiomyopathy
Chronic chagasic cardiomyopathy is a leading cause of heart failure in Latin American countries. About 30% of Trypanosoma cruzi-infected individuals develop this severe symptomatic form of the disease, characterized by intense inflammatory response accompanied by fibrosis deposition in the heart. We...
ORGANISM(S): Mus musculus 
2010-05-15 | E-GEOD-17363 | biostudies-arrayexpress
TranscriptomicsTrancriptome analysis of peripheral leukocytes from SARS-CoV-2 infected patients and healthy uninfected individuals during the first wave of COVID-19 pandemic in Brazil
To evaluate the gene expression profiling of peripheral leukocytes in different outcomes of SARS-CoV-2 infections, whole blood samples were collected from individuals with positive SARS-CoV-2 nasopharyngeal swab by RT-PCR (54 patients) and healthy uninfected individuals (12 volunteers). Infected pat...
ORGANISM(S): Homo sapiens 
2022-04-29 | E-MTAB-11240 | biostudies-arrayexpress
UnknownEarly Treatment with Pegylated Interferon Lambda for Covid-19.
Not available
S-EPMC9933926 | biostudies-literature
UnknownEffect of Early Treatment with Ivermectin among Patients with Covid-19.
Not available
S-EPMC9006771 | biostudies-literature
UnknownOral Fluvoxamine With Inhaled Budesonide for Treatment of Early-Onset COVID-19 : A Randomized Platform Trial.
Not available
S-EPMC10111398 | biostudies-literature
UnknownTwo Phase 3 Trials of Gantenerumab in Early Alzheimer's Disease.
Not available
S-EPMC10794000 | biostudies-literature
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