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TranscriptomicsAnalysis of DNA relaxation in Dickeya dadantii wild type, fis and hns strains
We have analyzed the transcriptomes of Dickeya dadantii wild type, fis and hns strains in condition of DNA relaxation induced by novobiocin, a DNA gyrase inhibitor. For DNA relaxation novobiocin was added for 15 min to 100µg/ml final concentration to exponentially growing wild type, hns and fis stra...
ORGANISM(S): Dickeya dadantii 
2015-04-16 | E-MTAB-2597 | biostudies-arrayexpress
TranscriptomicsCell-cycle regulation of cohesin stability along fission yeast chromosomes
Sister chromatid cohesion is mediated by cohesin but the process of cohesion establishment during S phase is still enigmatic. Recent data indicate that in mammalian cells, cohesin binding to chromatin is dynamic in G1 but becomes stabilized during S phase. Whether the regulation of chromosomal cohes...
ORGANISM(S): Schizosaccharomyces pombe 
2007-11-30 | E-GEOD-8450 | biostudies-arrayexpress
TranscriptomicsTranscriptional profiles from Dickeya dadantii 3937 in various growth conditions
We have analysed the global gene expression of the plant pathogen Dickeya dadantii 3937 when grown in vitro under different growth and stress conditions. A multi-factorial design with 32 different experimental conditions was constructed, with two biological replicates for each condition. Cells were ...
ORGANISM(S): Dickeya dadantii 3937 
2015-04-16 | E-MTAB-541 | biostudies-arrayexpress
TranscriptomicsEvidence of Late Pleistocene origin of Astyanax mexicanus cavefish
We found higher substitution rates in cavefish compared with surface fish, in accordance with a smaller cavefish population size which has allowed more rapid fixation of derived alleles present in the ancestral population. This result also implies that the Pachn cave population is much younger than ...
ORGANISM(S): Hyphessobrycon anisitsi 
2016-06-27 | E-MTAB-5142 | biostudies-arrayexpress
GenomicsGenomic binding of Pol III transcription machinery and relationship with TFIIS distribution in mouse embryonic stem cells
RNA polymerase (RNA Pol) III synthesizes the tRNAs, the 5S ribosomal RNA and a small number of untranslated RNAs. In vitro, it also transcribes short interspersed nuclear elements (SINEs). We investigated the distribution of RNA Pol III and its associated transcription factors on the genome of mouse...
ORGANISM(S): Mus musculus 
2011-09-16 | E-MTAB-767 | biostudies-arrayexpress
Transcriptomicsaffy_petaldvt_lyon_rose: Flower/Petal initiation and development in roses
affy_petaldvt_lyon_rose. The objective is to identify genes involved in petal development in rose. We aim at identifying genes whose expression correlates with flower opening and scent emission. In this study, we used a microarray approach to compare the transcriptome of a scented rose flower (PF) v...
ORGANISM(S): Rosa hybrid cultivar 
2011-08-31 | E-GEOD-18357 | biostudies-arrayexpress
TranscriptomicsTargetted Microarray Testing for Intellectual Disability Provides Diagnoses and Identifies Novel Candidate Genes
We designed a microarray to test at exonic resolution for genomic imbalance for genes representative of all known chromosomal microdeletion/microduplication syndromes, all known causative genes for ID, all known genes encoding glutamate receptors and their known encoding proteins and all known genes...
ORGANISM(S): Homo sapiens 
2012-07-23 | E-GEOD-39533 | biostudies-arrayexpress
TranscriptomicsCIT_VADS_BW_OMICS
A Cartes d'Identite des Tumeurs (CIT) project from the french Ligue Nationale Contre le Cancer (http://cit.ligue-cancer.net); Integrative study based on 89 patients with Head and Neck Squamous Cell Carcinoma (HNSCC); 89 Affymetrix HG-U133 Plus 2.0 GeneChips arrays; 88 samples on HumanCNV370-Quad Ge...
ORGANISM(S): Homo sapiens 
2013-01-30 | E-MTAB-1328 | biostudies-arrayexpress
TranscriptomicsMethylation profiling by array of 108 clear cell renal cell carcinoma
A Cartes d'Identite des Tumeurs (CIT) project from the French Ligue Nationale Contre le Cancer (http://cit.ligue-cancer.net). Selecting patients with metastatic clear-cell renal cell carcinoma (m-ccRCC) who might benefit from treatment wi...
ORGANISM(S): Homo sapiens 
2016-02-26 | E-MTAB-3274 | biostudies-arrayexpress
TranscriptomicsStudy of the molecular stability of patient-derived tumor xenograft (PDX) for human renal cell carcinoma (RCC) in nude mice during subsequent passages in mice
We established a large panel of preclinical models of human RCC directly from patients, faithfully reproducing the biological features of the original tumor. RCC tissues were collected for 8 years from 336 patients undergoing surgery, xenografted subcutaneously in nude mice, and serially passaged in...
ORGANISM(S): Homo sapiens 
2016-06-29 | E-GEOD-83820 | biostudies-arrayexpress
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