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ProteomicsQuantitative Proteomics Analysis of Placenta from Zika Virus Infected Women
Zika Virus (ZIKV) infection has been associated with fetal abnormalities by compromising placental integrity. Flavivirus have shown deregulation of the host proteome, specially extracellular matrix (ECM) proteins. Our hypothesis is that ZIKV infection of placental tissue deregulates specific ECM pro...
ORGANISM(S): Homo sapiens (Human) 
2022-06-09 | PXD023964 | Pride
Tandem mass tagging (tmt) Zika virus (zikv) Congenital zika syndrome (czs) 
ProteomicsToward the discovery of biological functions associated with the mechanosensor Mtl1p of Saccharomyces cerevisiae via integrative multi-OMICs analysis.
Functional analysis of the Mtl1 protein in Saccharomyces cerevisiae has revealed that this transmembrane sensor endows yeast cells with resistance to oxidative stress by hydrogen peroxide (H2O2) treatment through a signaling mechanism called the cell wall integrity pathway (CWI). Quantitative mRNA e...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2021-09-10 | PXD023963 | Pride
General stress response Metabolome Yeast mechanosensors Proteome Yeast cell wall integrity 
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