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UnknownThe oncometabolite D-2-hydroxyglutarate induced by mutant IDH1 or -2 blocks osteoblast differentiation in vitro and in vivo.
Not available
S-EPMC4558118 | biostudies-literature
TranscriptomicsCombined transcriptomics classifier analysis reveals a set of adverse effect genes for use as potential endpoint in effect based screening
Environmental risk assessment relies heavily on the use of bioassays to assess the environmental impact of chemicals. Gene expression is gaining acceptance as a valuable mechanistic endpoint in bioassays and effect-based screening. Data analysis and its results however, are often complex and not dir...
ORGANISM(S): Folsomia candida 
2015-11-09 | E-GEOD-70877 | biostudies-arrayexpress
TranscriptomicsClassifier analysis of gene expression profiles reveals a discriminatory gene set for soil containing different metals
Environmental pollution is a worldwide problem, and metals are the largest group of contaminants in soil. Microarray toxicogenomic studies with ecologically relevant organisms such as springtails, supplement traditional ecotoxicological research, but are presently rather descriptive. Classifier anal...
ORGANISM(S): Folsomia candida 
2010-02-04 | E-GEOD-19353 | biostudies-arrayexpress
TranscriptomicsAdaptive differences in gene expression associated with stress tolerance in the soil arthropod Orchesella cincta
Field-selected tolerance to heavy metals has been reported for Orchesella cincta (Arthropoda: Collembola) populations occurring at metal-contaminated mining sites. This tolerance is correlated with heritable increase of metal excretion efficiency; less pronounce cadmium induced growth reduction and,...
ORGANISM(S): Orchesella cincta 
2009-04-01 | E-GEOD-14076 | biostudies-arrayexpress
UnknownAlleviation of Microglial Activation Induced by p38 MAPK/MK2/PGE2 Axis by Capsaicin: Potential Involvement of other than TRPV1 Mechanism/s.
Not available
S-EPMC5428011 | biostudies-literature
TranscriptomicsGene expression microarray analysis of heat stress in the soil invertebrate Folsomia candida
Temperature is an important ecological condition, and sudden temperature changes in soil can induce stress in soil-dwelling invertebrates. Soil animals can move to more favorable habitats and/or adapt physiologically to a stressful environment. Hyperthermic conditions will impact gene expression as ...
ORGANISM(S): Folsomia candida 
2010-06-24 | E-GEOD-17024 | biostudies-arrayexpress
TranscriptomicsFunctional environmental genomics of a municipal landfill soil
We investigated the toxicity of soil samples derived from a former municipal landfill site in the South of the Netherlands, where a bioremediation project is running aiming at reusing the site for recreation. Both an organic soil extract and the original soil sample was investigated using the ISO st...
ORGANISM(S): Folsomia candida 
2012-04-15 | E-GEOD-37154 | biostudies-arrayexpress
TranscriptomicsSugar sweet springtails: On the transcriptional response of Folsomia candida (Collembola) towards desiccation stress
Folsomia candida (Collembola) is able to survive dryer conditions by absorbing water vapour from its surroundings. To unravel the genomic responses underlying this intriguing water-absorption mechanism, we exposed the species to 98.2% Relative Humidity (eight, 27, 53 and 174 hours respectively) and ...
ORGANISM(S): Folsomia candida 
2010-05-06 | E-GEOD-16127 | biostudies-arrayexpress
TranscriptomicsFolsomia candida exposed to soil containing different phenanthrene concentrations
Polycyclic aromatic hydrocarbons are common pollutants in soil, have negative effects on soil ecosystems, and are potentially carcinogenic. The Springtail (Collembola) Folsomia candida is often used as an indicator species for soil toxicity. Here we report a toxicogenomic study that translates the e...
ORGANISM(S): Folsomia candida 
2010-05-18 | E-GEOD-14207 | biostudies-arrayexpress
UnknownThe nucleotide changes governing cuticular hydrocarbon variation and their evolution in Drosophila melanogaster.
Not available
S-EPMC31154 | biostudies-literature
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