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ProteomicsNavigating the Complex Landscape of N-Glycoproteomics: Guidelines for Large-Scale Data Processing
Large-scale N-glycoproteomics remains challenging because the structural complexity and heterogeneity of glycans can lead to frequent misassignments in automated MS2-based glycopeptide annotation. In particular, isobaric and isomeric monosaccharide combinations, ammonia adducts, carbamidomethylation...
ORGANISM(S): Homo Sapiens 
PXD077279 | panorama
TranscriptomicsExpression data of human trophectoderm cells
The implantation process begins with attachment of the trophectoderm (TE) of the blastocyst to the maternal endometrial epithelium. Herein we have investigated the transcriptome of mural TE cells from 13 human blastocysts and compared these with those of human embryonic stem cell (hESC)-derived-TE (...
ORGANISM(S): Homo sapiens 
2011-09-08 | E-GEOD-30650 | biostudies-arrayexpress
ProteomicsScreening of protein carbonylation sites in human serum by ion mobility mass spectrometry
Excessive oxidative stress, which is associated with several diseases, can trigger oxidative protein modifications, including protein carbonylation, which refers to the oxidative formation of aldehyde or keto groups in proteins. The structural diversity of these non-enzymatic reactive carbonyl group...
ORGANISM(S): Homo Sapiens 
PXD058666 | panorama
ProteomicsPeptide centric detection of cross-linked peptides using PASEF, MeroX, and Skyline
Cross-linking mass spectrometry (XL-MS) has evolved into a pivotal technique for probing protein interactions, with recent ad-vancements significantly enhancing its analytical potential. This technical note presents advancements in cross-linking mass spec-trometry (XL-MS) through the implementation ...
ORGANISM(S): Bos Taurus 
PXD047307 | panorama
UnknownPrimary Ciliary Dyskinesia: Ancestral Haplotypes Analysis of the RSPH4A Founder Mutation in Puerto Rico.
Not available
S-EPMC8415044 | biostudies-literature
TranscriptomicsPerivascular Human Endometrial Mesenchymal Stem Cells Express Pathways Relevant to Self-Renewal, Lineage Specification, and Functional Phenotype
A population of endometrial cells displaying key properties of mesenchymal stem cells (eMSC) has been identified in human endometrium. eMSC co-express CD146 and PDGFRB surface markers, have a perivascular location, and likely represent the reservoir of progenitors giving rise to the endometrial str...
ORGANISM(S): Homo sapiens 
2011-11-14 | E-GEOD-31152 | biostudies-arrayexpress
ProteomicsMolecular details of ligand binding to the intrinsically disordered N terminus of the neuropeptide Y receptor
Neuropeptide Y (NPY) receptors comprise a family of rhodopsin-like G-protein coupled receptors (GPCRs) that participate in controlling food intake, memory retention, and circadian rhythm, making them highly attractive drug targets. However, the multiligand nature of NPY receptors, such as the NPY re...
ORGANISM(S): Homo Sapiens Escherichia Coli Sus Scrofa 
2026-03-24 | PXD051865 | panorama
ProteomicsAnalysis of N-Glycosylation for SARS-CoV-2 expressed receptor-binding domain VOCs and membrane protein with LC-MS.
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can infect human cells by first attaching to the ACE-2 receptor via its receptor-binding domain (RBD) in the spike protein. We investigated the influence of N-glycosylation sites of the RBD and the membrane (M) protein on IgG antibody bind...
ORGANISM(S): Severe Acute Respiratory Syndrome Coronavirus 2 
PXD048930 | panorama
UnknownTreatment of adult chronic indeterminate Chagas disease with benznidazole and three E1224 dosing regimens: a proof-of-concept, randomised, placebo-controlled trial.
Not available
S-EPMC7612561 | biostudies-literature
UnknownOpen-label phase I/II clinical trial of SARS-CoV-2 receptor binding domain-tetanus toxoid conjugate vaccine (FINLAY-FR-2) in combination with receptor binding domain-protein vaccine (FINLAY-FR-1A) in children.
Not available
S-EPMC9673084 | biostudies-literature
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