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TranscriptomicsGene expression data from T-cell progenitors developing in response to DLL4 stimulation in the plastic thymus
Since the first description of the involvement of Notch signaling in homeostasis especially of T cells, there is great effort in research to find new target genes of Notch that are involved in T cell development in the thymus. We developed a stroma cell free system that is able to induce T cell deve...
ORGANISM(S): Mus musculus 
2013-05-31 | E-GEOD-46191 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of seven consecutive stages of mouse thymocyte development
Expression profiles of seven consecutive stages of mouse thymocyte development were generated.
ORGANISM(S): Mus musculus 
2007-12-20 | E-GEOD-272 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human B cells at four cconsecutive stages of B cell development
Cells from four develppmental stages were purified by FACS from human bone marrow samples Experiment Overall Design: Cells were sorted as follows: PB1: CD34+VpreB+ PB2: VpreB-CD34+ LAR: kappa/lambda-VpreB-large SMA: kappa/lambda-VpreB-small. All cells were CD19+
ORGANISM(S): Homo sapiens 
2008-06-18 | E-GEOD-4590 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse B cells derived from bone marrow
Affymetrix GeneChip derived gene expression profiles of flow sorted murine B cell precursors, ex-vivo isolated, RNA-amplified
ORGANISM(S): Mus musculus 
2007-12-13 | E-GEOD-13 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse early B cells overexpressing OBF-1
OBF1, also known as Bob.1 or OCA-B, is a B lymphocyte-specific transcription factor which coactivates Oct1 and Oct2 on B cell specific promoters. So far, the function of OBF1 has been mainly identified in late stage B cell populations. The central defect of OBF1 deficient mice is a severely reduced ...
ORGANISM(S): Mus musculus 
2009-01-14 | E-GEOD-12421 | biostudies-arrayexpress
GenomicsGenome-wide maps of chromatin state in HSC, Pro B and mature B cells
We have used a genome-wide ChIP-sequencing approach to define and investigate the dynamics of the cis-regulatory landscape in three developmental stages of the murine hematopoietic system. To this end, we have compared the profiles of H3K4me3, H3K4me1, H3K27ac, H3K27me3 and H3K9me2 in HSCs, committe...
ORGANISM(S): Mus musculus 
2015-10-19 | E-GEOD-60005 | biostudies-arrayexpress
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