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TranscriptomicsGene regulation by phosphomimetic Myc (MycD), cytosine arabinoside (AraC) and retinoic acid (RA)
We aimed to investigate whether the previously observed synergistic effects of AraC and RA in stimulating leukemia differentiation could be at least partially dependent on Pak2-mediated phosphorylation of Myc. Genome-wide analysis of NB4 cells treated with RA, AraC with RA, or MycD with RA revealed ...
ORGANISM(S): Homo sapiens 
2012-01-05 | E-GEOD-29213 | biostudies-arrayexpress
TranscriptomicsGene regulation by phosphomimetic Myc and retinoic acid
We aimed to investigate the E-box and Max-independent functions of the oncogene Myc in gene regulation and differentiation of leukemic cells. Expression in HL60 leukemic cells of a mutant form of Myc with impaired Max and E-box interaction by replacing the phosphorylation sites of Pak2 kinase to asp...
ORGANISM(S): Homo sapiens 
2012-01-05 | E-GEOD-24731 | biostudies-arrayexpress
UnknownEmbodiment of underweight and normal-weight avatars affects bodily self-representations in anorexia nervosa.
Not available
S-EPMC11233954 | biostudies-literature
UnknownCysteine-based regulation of redox-sensitive Ras small GTPases.
Not available
S-EPMC6695279 | biostudies-literature
TranscriptomicsWidespread Generation of Alternative UTRs Contributes to Sex-specific RNA Binding by UNR
Upstream of N-ras (UNR) is a conserved RNA-binding protein that regulates mRNA translation and stability by binding to sites generally located in untranslated regions (UTRs). In Drosophila, sex-specific binding of UNR to msl2 mRNA and the non-coding RNA roX plays key roles in the control of X-chromo...
ORGANISM(S): Drosophila melanogaster 
2011-10-25 | E-GEOD-33178 | biostudies-arrayexpress
GenomicsYAP1 exerts its transcriptional control via TEAD mediated activation of enhancers
YAP is the principle effector of the Hippo signaling pathway; a key regulator of tissue homeostasis whose dysregulation is linked to cancer development. YAP regulation of gene expression is thought to involve the TEAD transcription factor family. Here we show that YAP and TEAD1 binding always co-occ...
ORGANISM(S): Homo sapiens 
2015-08-25 | E-GEOD-61852 | biostudies-arrayexpress
UnknownLigand binding to the FA3-FA4 cleft inhibits the esterase-like activity of human serum albumin.
Not available
S-EPMC4366387 | biostudies-literature
UnknownSpermine Oxidase-Substrate Electrostatic Interactions: The Modulation of Enzyme Function by Neighboring Colloidal ɣ-Fe2O3.
Not available
S-EPMC10742170 | biostudies-literature
UnknownArchaeal protoglobin structure indicates new ligand diffusion paths and modulation of haem-reactivity.
Not available
S-EPMC2246406 | biostudies-literature
Unknownp75NTR Modulation by LM11A-31 Counteracts Oxidative Stress and Cholesterol Dysmetabolism in a Rotenone-Induced Cell Model of Parkinson's Disease.
Not available
S-EPMC12496268 | biostudies-literature
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