Sort   by:  
 Page size 
TranscriptomicsTranscription profiling by array of mouse wild type and Fibroblast specific protein 1 expressing liver
The aim of this study was to investigate FSP1 in human and experimental liver disease, and to characterize FSP1-positive cells. Results: FSP1-positive cells are increased in human and experimental liver diseases including liver cancer but do not synthesize type I collagen or express other classical ...
ORGANISM(S): Mus musculus 
2010-12-14 | E-MTAB-287 | biostudies-arrayexpress
TranscriptomicsMicroarray correpsonding to the paper manuscript titled: Targeted expression profiling of single disseminated cancer cells isolated from bone marrow of prostate cancer patients
Bone is the most frequent site of metastasis in prostate cancer (PCa) and patients with bone metastases are deemed incurable. Targeting prostate cancer cells that disseminated to the bone marrow (BM) prior to surgery and before metastatic outgrowth may therefore prevent lethal metastasis. This promp...
ORGANISM(S): Homo sapiens 
2014-10-20 | E-GEOD-59631 | biostudies-arrayexpress
TranscriptomicsDAF-16/FoxO and EGL-27/GATA promote developmental growth in response to persistent somatic DNA damage [N2, daf-2, daf-16, daf-2;daf-16]
Genome maintenance defects cause complex disease phenotypes characterized by developmental failure, cancer susceptibility and premature aging. It remains poorly understood how DNA damage responses function during organismal development and maintain tissue functionality when DNA damage accumulates wi...
ORGANISM(S): Caenorhabditis elegans 
2014-11-18 | E-GEOD-51162 | biostudies-arrayexpress
ProteomicsDYRK1B blockade promotes tumoricidal macrophage activity in pancreatic cancer
Highly malignant pancreatic ductal adenocarcinoma (PDAC) is characterized by an abundant immunosuppressive and fibrotic tumor microenvironment (TME). Future therapeutic attempts therefore demand targeting of both compartments in order to be effective. We show here that Dual Specificity and Tyrosine...
ORGANISM(S): Mus Musculus 
2024-01-02 | MSV000093747 | MassIVE
GenomicsNational Human Genome Research Institute Tumor Sequencing Project (TSP) - Lung Adenocarcinoma

The Tumor Sequencing Project (TSP) Consortium is a collaboration among participants at the Baylor College of Medicine Human Genome Sequencing Center, the Broad Institute Genome Sequencing Platform, the Dana Farber Cancer Institute, the Memorial Sloan-Kettering Cancer Center, the Genome Seque...

phs000144.v1.p1 | EGA
GenomicsWhole Genome Association Study of Systemic Lupus Erythematosus

The goal of this collaborative study was to identify new genetic risk factors for Systemic Lupus Erythematosus (SLE). To do this we conducted a genome-wide scan by combining the resources and expertise from a number of SLE researchers to establish a large sample set comprising 1311...

phs000122.v1.p1 | EGA
TranscriptomicsDAF-16/FoxO and EGL-27/GATA promote developmental growth in response to persistent somatic DNA damage [N2, xpa-1]
Genome maintenance defects cause complex disease phenotypes characterized by developmental failure, cancer susceptibility and premature aging. It remains poorly understood how DNA damage responses function during organismal development and maintain tissue functionality when DNA damage accumulates wi...
ORGANISM(S): Caenorhabditis elegans 
2014-11-18 | E-GEOD-51161 | biostudies-arrayexpress
GenomicsComprehensive Transcriptional Analysis of Early Stage Urothelial Carcinoma using whole transcriptome sequencing
The expression profile and sequence variants of 476 early stage urothelial carcinoma were studied using whole transcriptome sequencing. RNA-Seq libraries were prepared by Ribo-Zero treatment of total-RNA followed by library preparation using ScriptSeq (both Epicentre/Illumina). RNA-Seq libraries wer...
EGAS00001001236 | EGA
UnknownIntegrative Analysis Identifies Four Molecular and Clinical Subsets in Uveal Melanoma.
Not available
S-EPMC5619925 | biostudies-literature
GenomicsComprehensive genomic profiles of small cell lung cancer
We have sequenced the genomes of 110 small cell lung cancers (SCLC), one of the deadliest human cancers. We found bi-allelic inactivation of TP53 and RB1 in nearly all the tumors analyzed, sometimes by complex genomic rearrangements. Two tumors with wild-type RB1 had evidence of chromothripsis leadi...
EGAS00001000925 | EGA
Sort   by:  
 Page size