Sort   by:  
 Page size 
TranscriptomicsGene expression changes in U937 cells in response to ectopic expression of EVI1 and/or etoposide treatment
Overexpression of ecotropic viral integration site 1 (EVI1) is associated with aggressive disease in acute myeloid leukemia (AML). Despite of its clinical importance, little is known about the mechanism through which EVI1 confers resistance to antileukemic drugs. Here, we show that a human myeloid c...
ORGANISM(S): Homo sapiens 
2015-03-10 | E-GEOD-66660 | biostudies-arrayexpress
TranscriptomicsEVI1 promotes tumor growth via transcriptional repression of MS4A3
Background: The transcription factor EVI1 regulates cellular proliferation, differentiation, and apoptosis, and contributes to an aggressive course of disease in myeloid leukemias and other malignancies. Notwithstanding, knowledge about the target genes mediating its biological and pathological func...
ORGANISM(S): Homo sapiens 
2015-08-30 | E-GEOD-60100 | biostudies-arrayexpress
Sort   by:  
 Page size