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TranscriptomicsIntegrative genomic approach reveals expression of intronic miR-335, miR-342, and miR-561 in multiple myeloma
The role of microRNAs (miRNAs) in multiple myeloma (MM) has yet to be fully elucidated. To identify miRNAs that are potentially deregulated in MM, we investigated those mapping within transcription units, based on evidence that intronic miRNAs are frequently coexpressed with their host genes. To thi...
ORGANISM(S): Homo sapiens 
2008-11-10 | E-GEOD-11522 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human myeloma cell lines (23)
In order to investigate the patterns of genetic lesions in a panel of 23 Human Multiple Myeloma Cell Lines (HMCLs), we made a genomic integrative analysis involving FISH and both gene expression and genome-wide profiling approaches. The expression profiles of the genes targeted by the main IGH trans...
ORGANISM(S): Homo sapiens 
2008-06-14 | E-GEOD-6205 | biostudies-arrayexpress
TranscriptomicsSmall nucleolar RNAs as new biomarkers in chronic lymphocytic leukemia
Small nucleolar RNAs (snoRNAs) and small Cajal body-specific RNAs are non-coding RNAs involved in the maturation of other RNA molecules. Alterations of sno/scaRNA expression may play a role in cancerogenesis. This study elucidates the patterns of sno/scaRNA expression in highly purified cells from 2...
ORGANISM(S): Homo sapiens 
2014-03-24 | E-GEOD-46261 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human bone marrow endothelial cells in patients with multiple myeloma
To determine a gene/molecular fingerprint of multiple myeloma (MM) endothelial cells (MMECs), also identifying some of the vascular mechanisms that govern the malignant progression from quiescent monoclonal gammopathy of undetermined significance (MGUS). A comparative gene expression profiling (GEP)...
ORGANISM(S): Homo sapiens 
2009-09-15 | E-GEOD-14230 | biostudies-arrayexpress
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