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TranscriptomicsTranscription profiling of rat non-alcoholic Steatohepatitis following feeding of high polyunsaturated fat diets
Most commonly used models of non-alcoholic steatohepatitis (NASH) are diets based on specific gene knockouts or represent extreme manipulations of diet. We have examined the effects of modest increased caloric intake and high dietary unsaturated fat content on the development of NASH in male rats us...
ORGANISM(S): Rattus norvegicus 
2008-06-20 | E-GEOD-8253 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of rat liver to investigate ethanol induced hepatic gene expression changes during gestation
The specific role of nutritional status during gestation in exacerbating or mitigating fetal toxicity of ethanol (EtOH) remains unclear. We used an intragastric infusion model (Total enteral nutrition, TEN) to appropriately control for dietary EtOH consumption and caloric intake. Time impregnated fe...
ORGANISM(S): Rattus norvegicus 
2008-06-12 | E-GEOD-3740 | biostudies-arrayexpress
TranscriptomicsFemale Mice Lacking p47phox Have Altered Adipose Tissue Gene Expression and are Protected against High Fat-Induced Obesity and Metabolic Syndrome
Oxidative stress in adipose tissue and liver has been linked to the development of obesity. NADPH oxidases (NOX) enzymes are a major source of reactive oxygen species (ROS). The current study was designed to determine if NOX2-generated ROS play a role in development of obesity and metabolic syndrom...
ORGANISM(S): Mus musculus 
2012-11-01 | E-GEOD-41932 | biostudies-arrayexpress
TranscriptomicsBlueberry Diets during Early Development Only Is Sufficient to Prevent Senescence of Osteoblasts and Bone Loss in Adulthood
Appropriate nutrition during early development is essential for optimal bone mass accretion; however, linkage between early nutrition, childhood bone mass and prevention of bone loss later in life has not been extensively studied. In this report, we have demonstrated several fundamental issues in th...
ORGANISM(S): Rattus norvegicus 
2012-06-30 | E-GEOD-30081 | biostudies-arrayexpress
TranscriptomicsChanges in mammary gene expression and morphology following consumption of soy protein isolate in female Sprague-Dawley rats differs from that produced by 17b-estradiol treatment
Soy foods have been suggested to have both positive health benefits and potentially adverse effects largely as a result of their content of isoflavone phytoestrogens. Since soy protein isolate (SPI) contains isoflavones, in addition to purported health benefits, safety concerns have been raised rega...
ORGANISM(S): Rattus norvegicus 
2012-05-21 | E-GEOD-38060 | biostudies-arrayexpress
UnknownOdd Chain Fatty Acids; New Insights of the Relationship Between the Gut Microbiota, Dietary Intake, Biosynthesis and Glucose Intolerance.
Not available
S-EPMC5362956 | biostudies-literature
UnknownInternational Consensus for the Dosing of Corticosteroids in Childhood-Onset Systemic Lupus Erythematosus With Proliferative Lupus Nephritis.
Not available
S-EPMC8766607 | biostudies-literature
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