Sort   by:  
 Page size 
UnknownStructures of human cytochrome P450 1A1 with bergamottin and erlotinib reveal active-site modifications for binding of diverse ligands.
Not available
S-EPMC6302172 | biostudies-literature
ProteomicsDairying supported prehistoric occupation of the highland Tibetan Plateau
The extreme environments of the Tibetan Plateau offer significant challenges to human survival, demanding novel adaptations. While the role of biological and agricultural adaptations in enabling early human colonization of the plateau has been widely discussed, the contribution of pastoralism is les...
ORGANISM(S): Homo sapiens (Human) 
2023-03-15 | PXD028538 | Pride
Tibetan plateau Paleoproteomics High-altitude adaptation Dairy pastoralism 
MetabolomicsNPC1 regulates the distribution of phosphatidylinositol 4 kinases at Golgi and Lysosome membranes
Cholesterol and phosphoinositides (PI) are two critically important lipids that are found in cellular membranes and dysregulated in many disorders. Therefore, uncovering molecular pathways connecting these essential lipids may offer new therapeutic insights. We report that loss of function of lysoso...
2021-09-15 | MTBLS2612 | MetaboLights
TranscriptomicsGene Expression Profiling of the Calvaria from Conditional Hdac3 Defecient and Wild-type Mice
We utilized the Illumina MouseRef-8 gene expression technology to quantify differential gene expression between wildtype mice and mice with Osterix driven Cre conditional knockout of Hdac3 (Hdac3-CKO). We compared the RNA extracted from calvaria from 8 wildtype and 8 conditional knockout litter mat...
ORGANISM(S): Mus musculus 
2010-04-07 | E-GEOD-21087 | biostudies-arrayexpress
TranscriptomicsProfiling the transcriptome of the adult mouse skeleton: RNA-seq of osteocytes from tibiae, femora, humeri and calvariae
In this experiment we define the transcriptome of the adult mouse skeleton by performing total-RNA transcriptome-sequencing on osteocytes, the critical regulatory cells in bone. Osteocytes from 16 week-old male mice (n=8) were isolated for 4 bone types across the skeleton: the tibia, femur, humerus,...
ORGANISM(S): Mus musculus 
2020-12-16 | E-MTAB-5532 | biostudies-arrayexpress
TranscriptomicsThe osteocyte transcriptome during post-natal skeletal maturation in male and female mice
These data examine the total-RNA transcriptome of primary osteocytes in both genders at 4 different stages of skeletal maturation. These stages are prepuberty (4 weeks), post puberty (10 weeks), early skeletal maturation (16 weeks), established skeletal maturation (26 weeks). These data were used to...
ORGANISM(S): Mus musculus 
2020-12-16 | E-MTAB-7447 | biostudies-arrayexpress
Sort   by:  
 Page size