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TranscriptomicsRNAi-mediated silencing of MLL-AF9 reveals leukemia-associated downstream targets and processes
The translocation t(9;11)(p22;q23) leading to the leukemogenic fusion gene MLL-AF9 is a frequent translocation in infant acute myeloid leukemia (AML). This study aimed to identify genes and molecular processes downstream of MLL-AF9 (alias MLL-MLLT3) which could assist to develop new targeted therapi...
ORGANISM(S): Homo sapiens 
2014-02-13 | E-GEOD-36592 | biostudies-arrayexpress
TranscriptomicsMiR-511 dependently expressed genes in monoblastic cell line THP1
To experimentally investigate the function of hsa-miR-511-5p in AML monoblasts, we employed miRNA mimic mediated up-regulation of miR-511 in THP1 cells and subsequently analyzed a comprehensive gene expression profile. 4 samples of two independent miRNA mimic experiments were analyzed. THP1 monoblas...
ORGANISM(S): Homo sapiens 
2016-01-16 | E-GEOD-70490 | biostudies-arrayexpress
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