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UnknownTo detect the heparan sulfate proteoglycans (HSGP) core proteins that are expressed in these cell lines, so that candidates for the Sulf-2 substrate can be identified
Not available
ORGANISM(S): Homo sapiens 
S-ECPF-GEOD-31935 | biostudies-other
TranscriptomicsTo detect the heparan sulfate proteoglycans (HSGP) core proteins that are expressed in these cell lines, so that candidates for the Sulf-2 substrate can be identified
We are requesting a gene microarray analysis for 10 cell lines that are pertinent to human non-small lung cancer. A main focus of ours has been the role that Sulf-2 plays in non-small cell lung cancer (NSCLC). Sulf-2 is an extracellular sulfatase that acts on internal glucosamine-6-sulfates within...
ORGANISM(S): Homo sapiens 
2011-09-05 | E-GEOD-31935 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by array of human myeloma cell lines
30 human myeloma cell lines
ORGANISM(S): Homo sapiens 
2010-12-23 | E-TABM-1088 | biostudies-arrayexpress
MetabolomicsFeatures of acute COVID-19 associated with post-acute sequelae of SARS-CoV-2 phenotypes: results from the IMPACC study
Post-acute sequelae of SARS-CoV-2 (PASC) is a significant public health concern. We describe Patient Reported Outcomes (PROs) on 590 participants prospectively assessed from hospital admission for COVID-19 through one year after discharge. Modeling identified 4 PRO clusters based on reported deficit...
2024-01-12 | MTBLS850 | MetaboLights
UnknownAn Ixodes scapularis Protein Disulfide Isomerase Contributes to Borrelia burgdorferi Colonization of the Vector.
Not available
S-EPMC7671890 | biostudies-literature
UnknownDaratumumab induces CD38 internalization and impairs myeloma cell adhesion.
Not available
S-EPMC6169590 | biostudies-literature
TranscriptomicsImpact of Glucocorticoids and PI3K Inhibition on Gene Expression in Myeloma
We previously noted that combination glucocorticoids and PI3K inhibition induces synergistic cell death. To identify genes involved in myeloma cell death we examined mRNA expression in each individual treatment and in the combination. The glucocoriticoid resistant cells (MM.1RL) are used as a nega...
ORGANISM(S): Homo sapiens 
2015-12-07 | E-GEOD-64704 | biostudies-arrayexpress
TranscriptomicsIdentification of p38 beta as a therapeutic target for the treatment of Sézary Syndrome
Cutaneous T-Cell Lymphomas (CTCL) represent a group of hematopoietic malignancies that home to the skin and have no known molecular basis for disease pathogenesis. Sézary syndrome (SS) is the leukemic variant of CTCL. Currently, CTCL is incurable, highlighting the need for new therapeutic modalitie...
ORGANISM(S): Homo sapiens 
2015-07-01 | E-GEOD-59179 | biostudies-arrayexpress
TranscriptomicsIntegrative Gene Expression Profiling Reveals G6PD-Mediated Resistance to RNA-Directed Nucleoside Analogues in B-Cell Neoplasms
8-amino-adenosine (8-NH2-Ado) inhibits RNA synthesis and specifically inhibits synthesis of mRNAs with short half-lives. We hypothesize that the mRNAs affected code for proteins important in apoptosis and glucose metabolism. Gene Expression Arrays will help us understand which gene families may be...
ORGANISM(S): Homo sapiens 
2012-05-31 | E-GEOD-38145 | biostudies-arrayexpress
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