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TranscriptomicsTranscription profiling by array of Streptococcus agalactiae strain 2603 V/R and isogenic Delta_csrRS mutant grown in the presence or in the absence of glucose
Comparative global gene expression analysis of the 2603 V/R Streptococcus agalactiae (Group B streptococcus, GBS) strain grown in a medium devoid of sugars versus bacteria incubated for 30 min in 55 mM glucose medium. To investigate whether glucose-dependent regulation of gene expression was modulat...
ORGANISM(S): Streptococcus agalactiae 
2013-07-15 | E-MTAB-1100 | biostudies-arrayexpress
ProteomicsProteomic Investigation of EVLP Tissue Lung Lobes
The aim of this work concerns the development of a proteomics workflow based on LC-MS/MS useful for a comprehensive study of molecular mechanisms related to the effect on the lung subjected to EVLP
ORGANISM(S): Rattus norvegicus (Rat) 
2018-11-28 | PXD006692 | Pride
Lung Evlp Proteomics 
TranscriptomicsUnderstanding toxicity pathways of gold nanoparticles: RNA expression study on Caco-2 human colon carcinoma cells
A safer design and higher eficacy of nano-gold therapeutic formulations requires examination of cellular responses to gold nanoparticles (AuNPs). In this work we compared cellular uptake, cytotoxicity and RNA expression patterns induced in Caco-2 cells of citrate-stabilized Au NP of two different si...
ORGANISM(S): Homo sapiens 
2015-01-22 | E-GEOD-55349 | biostudies-arrayexpress
TranscriptomicsSLAMF1/CD150 regulates chemotaxis, autophagy and therapy responses in chronic lymphocytic leukemia patients
This work shows that signaling-lymphocytic-activation-molecule-1 (SLAMF1), a co-stimulatory molecule and a microbial sensor, is expressed by normal CD19+/CD5+ B-lymphocytes. Its expression is lost in a subset of patients with chronic lymphocytic leukemia (CLL) characterized by an aggressive form of ...
ORGANISM(S): Homo sapiens 
2015-05-23 | E-GEOD-69165 | biostudies-arrayexpress
TranscriptomicsExpression data from untreated and ATP treated AML blasts
In the present study, we investigated whether, and to what extent, P2Rs and their ligands are involved in the regulation of AML cells. Our findings show that AML blasts express several receptors belonging to the P2X and P2Y family. Although different samples respond differently to ATP and UTP stimul...
ORGANISM(S): Homo sapiens 
2012-02-25 | E-GEOD-30903 | biostudies-arrayexpress
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