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TranscriptomicsExpression data from adult mouse cortex harvested at two different zeitgeber (ZT) timepoints of the 24h cycle
Gene expression in forebrain structures change during day and night depending on circadian and rest-activity cycles. Clock genes have been shown to be involved in the control of circadian and sleep-wake control. In this study, we aimed at studying the consequences of loss of SHARP1 (DEC2/BHLHE40) an...
ORGANISM(S): Mus musculus 
2014-11-21 | E-GEOD-59941 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of brain from mice with ischemia of the right common carotid artery or sham treated and then exposed to hypoxic conditions
Animals were anaesthetized with halothane (4% in 70% N2O: 30% O2). A small incision was made in the neck and the right common carotid artery was exposed and ligated with 4-0 surgical silk in three separate locations. The incision was closed, and the animal allowed to recover with access to food an...
ORGANISM(S): Mus musculus 
2007-11-13 | E-MEXP-1253 | biostudies-arrayexpress
ProteomicsCell-type and brain-region resolved mouse brain proteome
To understand the complexity of the brain, connectome and transcriptome maps of high resolution are being generated, but an equivalent catalogue of the brain proteome is lacking. To provide a starting point, we have performed an in-depth proteome analysis of the adult mouse brain, its major regions ...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2020-02-08 | MSV000084941 | MassIVE
TranscriptomicsInhibition of phosphodiesterase-4 promotes oligodendrocyte precursor cell differentiation and enhances CNS remyelination
We used transcription-profiling to identify mitogen-activated protein kinase (Mapk) signaling as an important regulator involved in the differentiation of oligodendrocyte progenitor cells (OPCs) into oligodendrocytes. We show in tissue culture that activation of Mapk signaling by elevation of intrac...
ORGANISM(S): Rattus norvegicus 
2013-08-29 | E-GEOD-50042 | biostudies-arrayexpress
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