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TranscriptomicsEffects of dietary curcumin on the colon proteome and transcriptome in the Mdr1a-/- mouse model of inflammatory bowel disease
This study assessed gene expression changes associated with inflammation in the colon tissue of multi-drug resistance targeted mutation (Mdr1a-/-) mice, a model of human IBD. It also tested the anti-inflammatory potential of curcumin in the colon of these mice with a particular focus on the proteome...
ORGANISM(S): Mus musculus 
2014-10-02 | E-GEOD-61939 | biostudies-arrayexpress
TranscriptomicsPost-weaning selenium and folate supplementation affects gene and protein expression and global DNA methylation in mice fed high-fat diets
Background: Consumption of high fat diets has negative impacts on health and well-being, some of which may be epigenetically regulated. Selenium and folate are two compounds which influence epigenetic mechanisms. We investigated the hypothesis that post-weaning supplementation with adequate levels o...
ORGANISM(S): Mus musculus 
2013-06-01 | E-GEOD-43038 | biostudies-arrayexpress
TranscriptomicsThe effects of kiwifruit extracts on colonic gene and protein expression levels in interleukin 10 gene-deficient mice.
Inflammatory Bowel Disease (IBD) is a term describing a collection of conditions characterised by chronic inflammatory disorder of the gastrointestinal tract involving an inappropriate immune response to commensal microorganisms in a genetically susceptible host. Four kiwifruit extracts, aqueous and...
ORGANISM(S): Mus musculus 
2011-03-05 | E-GEOD-27684 | biostudies-arrayexpress
TranscriptomicsGene expression changes in the microdissected colon epithelium are similar to those of intact colon in the Il10-/- mouse model of IBD
Epithelial cells play an important role in the protection of the colon mucosa from the resident microbiota and are involved in the initiation and maintenance of intestinal inflammation. LMD is a technique that allows the extraction of specific cell types, such as colonic epithelial cells, to analyse...
ORGANISM(S): Mus musculus 
2013-03-01 | E-GEOD-39859 | biostudies-arrayexpress
UnknownPerformance evaluation of automated white matter hyperintensity segmentation algorithms in a multicenter cohort on cognitive impairment and dementia.
Not available
S-EPMC9877422 | biostudies-literature
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