Sort   by:  
 Page size 
Ribosomal protein RPL26 is the principal target of UFMylation
UFM1 is a small, metazoan-specific, ubiquitin-like protein modifier that is essential for embryonic development. Although loss-of-function mutations in UFM1 conjugation are linked to ER stress, neither the biological function nor the relevant cellular targets of this protein modifier are known. Here...
ORGANISM(S): Homo sapiens 
2018-12-11 | GSE123539 | GEO
Genomics
RPL26 and gut
TP53 is mutated in 50% of all cancers, and is often functionally compromised in cancers where it is not mutated. We demonstrate that the pro-tumorigenic/metastatic Six1 homeoprotein decreases p53 levels through a mechanism that does not involve the negative regulator of p53, MDM2. Instead, Six1 regu...
ORGANISM(S): Mus musculus 
2016-01-15 | GSE65200 | GEO
TP53 is mutated in 50% of all cancers, and is often functionally compromised in cancers where it is not mutated. We demonstrate that the pro-tumorigenic/metastatic Six1 homeoprotein decreases p53 levels through a mechanism that does not involve the negative regulator of p53, MDM2. Instead, Six1 regu...
ORGANISM(S): Mus musculus 
2016-03-21 | GSE65677 | GEO
Sort   by:  
 Page size