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MetabolomicsFunctional potential of gut microbiota in Rhinolophus ferrumequinum revealed by 16S rRNA sequencing and metabolomics
Insectivorous bats depend on insects while sustaining high-energy flight and specialised immune tolerance. Gut microbiota may contribute to host energy utilisation and immune regulation, but their functions remain unclear. We investigated the greater horseshoe bat (Rhinolophus ferrumequinum) using 1...
2026-09-13 | MTBLS14955 | MetaboLights
MetabolomicsAppropriate taxonomic classification of intestinal microbiome by 16S rRNA gene targeting metagenomic approach
16S metagenomic analysis has provided much information about the intestinal microbiome. However, there are no reports that describe their appropriate taxonomic classification rank. Moreover, studies differ on the taxonomic ranking of the same microorganism. Intestinal microbiome exerts a significant...
2017-02-20 | MTBLS376 | MetaboLights
MetabolomicsDysbiosis of Gut Microbiota and Metabolomic Alterations in Myasthenia Gravis: Insights from 16S rRNA Sequencing and Untargeted Metabolomics

Background: Myasthenia gravis (MG) is an autoimmune disorder of neuromuscular transmission. Gut dysbiosis has been implicated in autoimmune pathogenesis, yet integrated microbial and metabolomic profiling in MG remains scarce.

Objectives:  To characterize gut microbiota and t...

2026-04-13 | MTBLS14266 | MetaboLights
MetabolomicsPolicosanol Alleviates Chronic Stress-Induced Growth Impairment via Gut Microbiota-Metabolite Interactions: Insights from 16S rRNA Sequencing and LC-MS Metabolomics

Background/Objectives: Policosanol, a bioactive compound derived from rice bran wax, has demonstrated potential for alleviatingshown potential in combating stress, yet its underlying mechanisms remain elusive. This study aimed to elucidate its role in mitigating chronic stress-induced growth impa...

2025-10-21 | MTBLS13189 | MetaboLights
MetabolomicsMetabolomics and 16S rRNA sequencing of human colorectal cancers and adjacent mucosa
Not available
ORGANISM(S): Homo sapiens 
ST001087 | MetabolomicsWorkbench
MetabolomicsA Combined LC-MS Metabolomics- and 16S rRNA Sequencing Platform to Assess Interactions between Herbal Medicinal Products and Human Gut Bacteria in Vitro: a Pilot Study on Willow Bark Extract
Herbal preparations are complex mixtures of natural products, many of which are able to reach the distal gut. There, they influence the microbial communities, and can be metabolized into bioactive metabolites. The aim of this study was to establish an interdisciplinary platform to unravel interactio...
2017-12-14 | MTBLS479 | MetaboLights
MetabolomicsRevealing the Social Biomarkers of Residual Feed Intake by Using 16s rRNA and LC-MS/MS in Duroc Pig
Not available
ORGANISM(S): Sus scrofa 
ST002210 | MetabolomicsWorkbench
TranscriptomicsrRNA cleavage ensures translational cessation in the mature sperm
We report how unique RNA seq profiles of ribosomal RNA (18S, 28S) present in sperm indicate specific cleavage sites. Additionally, these sequencing results reveal how overall character of RNA (GC content) can significantly affect overall distribution of mapped reads. Examination of rRNA population ...
ORGANISM(S): Homo sapiens 
2013-03-11 | E-GEOD-29160 | biostudies-arrayexpress
ProteomicsThe integrated stress response regulates 18S nonfunctional rRNA decay in mammals
Abstract - 18S nonfunctional rRNA decay (NRD) detects and eliminates translationally nonfunctional 18S rRNA. While this process is critical for ribosome quality control, the mechanisms underlying nonfunctional 18S rRNA turnover remain elusive, particularly in mammals. Here, we show that mammalian 18...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2024-12-09 | MSV000096620 | MassIVE
TranscriptomicsRNA-Seq of rRNA depleted circulating endothelial progenitor cells (cEPCs) in trisomy 21 and euploid samples
Massive-scale RNA-seq on rRNA-depleted samples allowed us to survey in a specific cell type, affected in Down syndrome, the complete set of coding and non-coding RNA species - emerging as novel contributors to pathogenic mechanisms - to an unprecedented level of resolution and sensitivity. In partic...
ORGANISM(S): Homo sapiens 
2011-05-04 | E-GEOD-27443 | biostudies-arrayexpress
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