Rtks - OmicsDI

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CRUK - Beatson Institute for Cancer Research - Switchback Rd, Bearsden, Glasgow G61 1BD - United Kingdom (2)
CRUK - Scotland Institute - Switchback Rd, Bearsden, Glasgow G61 1BD - United Kingdom (2)
Faculty of Biology, Medicine & Health, Manchester Cell-Matrix Centre, Manchester Academic Health Science Centre, University of Manchester, Michael Smith Building, Oxford Road, Manchester, M13 9PT, United Kingdom (2)
Associate Professor, Head Cancer Proteomics Group, University of Queensland Diamantina Institute, Woolloongabba, QLD, 4102 (1)
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Centre de recherche du Centre Hospitalier Universitaire (CHU) de Quebec-Université Laval, Québec, QC, Canada Centre de recherche sur le cancer de l’Université Laval, Québec, QC, Canada PROTEO-Quebec Network for Research on Protein Function, Engineering, and Applications, Québec, QC, Canada Department of Molecular Biology, Medical Biochemistry and Pathology, Université Laval, Québec, QC, Canada (1)
Columbia University, Department of Biochemistry and Molecular Biophysics, USA (1)
Core Unit Proteomics, Berlin Institute of Health at Charité – Universitätsmedizin Berlin and Max Delbrück Center for Molecular Medicine (MDC), Berlin Germany (1)
Department of Biological Engineering Massachusetts Institute of Technology Cambridge MA 02139, Koch Institute for Integrative Cancer Research Massachusetts Institute of Technology Cambridge MA 02142 USA, Center for Precision Cancer Medicine Massachusetts Institute of Technnology Cambridge MA 02142 USA (1)
Dept. of Medical Biochemistry and Cell Biology Institute of Biomedicine The Sahlgrenska Academy at the University of Gothenburg SWEDEN (1)
Division of Molecular and Cellular Functions School of Biological Sciences FBMH The University of Manchester (1)
Donnelly Centre, Department of Molecular Genetics,Department of Biochemistry,University of Toronto, Ontario, Canada (1)
Institute of Molecular Systems Biology Department of Biology ETH Zurich (1)
Max Delbruck Center for Molecular Medicine, BIH at Charite, Proteomics Core Facility, Robert-Roessle-Str. 10, 13125 Berlin (1)
Medicity Research Laboratories and Institute of Biomedicine, Faculty of Medicine, University of Turku, 20520 Turku, Finland. Turku Bioscience Centre, University of Turku and Åbo Akademi University, 20520 Turku, Finland. Department of Oncology, Turku University Hospital, 20521 Turku, Finland. (1)
Medicity Research Laboratories and Institute of Biomedicine, Faculty of Medicine, University of Turku, Finland Turku Bioscience Center, University of Turku and Åbo Akademi University, Finland (1)
Medizinisches Proteom-Center, Ruhr-Universität Bochum, Germany (1)
Novo Nordisk Foundation Center for Protein Research University of Copenhagen Faculty of Health and Medical Sciences Blegdamsvej 3B København N (1)
Professor of Biochemistry, Faculty of Biology, Medicine & Health, Manchester Cell-Matrix Centre, Manchester Academic Health Science Centre, University of Manchester, Michael Smith Building, Oxford Road, Manchester, M13 9PT, United Kingdom (1)
Program in Cancer and Stem Cell Biology, Duke-NUS Medical School, Singapore Department of Pediatrics, Duke University School of Medicine, Durham, NC, USA (1)
Proteomics, Metabolomics & Mass Spectrometry Laboratory, Institute for the Animal Production System in the Mediterranean Environment (ISPAAM), National Research Council, Piazzale Enrico Fermi 1, 80055 Portici (NA), Italy (1)
Sapporo Medical University School of Medicine (1)
The Novo Nordisk Foundation Center for Protein Research, University of Copenhagen, Denmark (1)
The State Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan, Hubei, China (1)
Yale Cancer Biology Institute (1)

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How Do Gangliosides Regulate RTKs Signaling?

Not available

S-EPMC3972652 | biostudies-literature

Oncogenic RTKs sensitize cancer cells to ferroptosis via c-Myc mediated upregulation of ACSL4.

Not available

S-EPMC11603294 | biostudies-literature

Proteome-Wide Detection and Annotation of Receptor Tyrosine Kinases (RTKs): RTK-PRED and the TyReK Database.

Not available

S-EPMC9953206 | biostudies-literature

Immunohistochemical analysis of RTKs expression identified HER3 as a prognostic indicator of gastric cancer.

Not available

S-EPMC4317956 | biostudies-literature

On a mechanistic impact of transmembrane tetramerization in the pathological activation of RTKs.

Not available

S-EPMC10192832 | biostudies-literature

MicroRNA-122 supports robust innate immunity in hepatocytes by targeting the RTKs/STAT3 signaling pathway

MicroRNA-122 (miR-122) is the most abundant microRNA in hepatocytes and a central player in liver biology and disease. Herein, we report a previously unknown role for miR-122 in hepatocyte intrinsic innate immunity. Restoring miR-122 levels in hepatoma cells markedly enhanced the activation of inter...

ORGANISM(S): Homo sapiens

2019-02-02 | GSE99663 | GEO

MicroRNA-122 supports robust innate immunity in hepatocytes by targeting the RTKs/STAT3 signaling pathway.

Not available

S-EPMC6389286 | biostudies-literature

Evodiamine Inhibits Colorectal Cancer Growth via RTKs Mediated PI3K/AKT/p53 Signaling Pathway.

Not available

S-EPMC10937270 | biostudies-literature

TGFβ signaling confers sorafenib resistance via induction of multiple RTKs in hepatocellular carcinoma cells.

Not available

S-EPMC5712429 | biostudies-literature

EGFR/MET promotes hepatocellular carcinoma metastasis by stabilizing tumor cells and resisting to RTKs inhibitors in circulating tumor microemboli.