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TranscriptomicsAccumulation of inorganic polyphosphate mediates metabolic downshift and antibiotic tolerance in Mycobacterium tuberculosis
The stringent response, involving the regulatory molecules inorganic polyphosphate (poly P) and (p)ppGpp, is believed to mediate Mycobacterium tuberculosis persistence. In this study, we identified a novel exopolyphosphatase responsible for poly P hydrolysis. Using two different poly P-accumulating ...
ORGANISM(S): Mycobacterium tuberculosis CDC1551 
2015-02-20 | E-GEOD-57868 | biostudies-arrayexpress
UnknownMobile Phone Ownership Is Not a Serious Barrier to Participation in Studies: Descriptive Study.
Not available
S-EPMC5838361 | biostudies-literature
TranscriptomicsTMPRSS2-ERG fusion prostate cancer is a molecularly distinct estrogen-sensitive subclass of aggressive prostate cancer
Common epithelial cancers are believed to become more aggressive through the accumulation of multiple independent molecular events that lead to the deregulation of cell signaling. However, the discovery that the majority of prostate cancers harbor gene fusions of the 5'-untranslated region of androg...
ORGANISM(S): Homo sapiens 
2008-05-27 | E-GEOD-8402 | biostudies-arrayexpress
UnknownThe Moment Study: protocol for a mixed method observational cohort study of the Alternative Nicotine Delivery Systems (ANDS) initiation process among adult cigarette smokers.
Not available
S-EPMC4854005 | biostudies-literature
TranscriptomicsmiR-193a-3p is a key tumor-suppressor in ulcerative colitis-associated colon cancer and promotes carcinogenesis through regulation of IL17RD.
Patients with ulcerative colitis (UC) are at increased risk for colorectal cancer although mechanisms remain poorly understood. We sought to evaluate the role of miRNAs in neoplasia development in this high-risk population RNA was extracted from formalin fixed paraffin embedded tissue from  controls...
ORGANISM(S): Homo sapiens 
2015-04-28 | E-GEOD-68306 | biostudies-arrayexpress
TranscriptomicsIdentification of humoral signature for prostate cancer
High-density phage epitope microarray from 31 samples were used for unsupervised analysis (GSM36153...GSM36183). 129 samples from prostate cancer patients and controls were screened on small focused epitope chips, which contained 180 phage elements. These data were used to train GA/KNN program (GSM...
ORGANISM(S): Homo sapiens 
2005-10-04 | E-GEOD-2010 | biostudies-arrayexpress
UnknownThe World Health Network: a global citizens' initiative.
Not available
S-EPMC8553262 | biostudies-literature
TranscriptomicsMouse alveolar rhabdomyosarcoma and wild-type skeletal muscle
The highly aggressive muscle cancer alveolar rhabdomyosarcoma (ARMS) is one of the most common soft tissue sarcoma of childhood, yet the outcome for unresectable and metastatic disease is dismal and unchanged for nearly 3 decades. To better understand the pathogenesis of this disease and to facilita...
ORGANISM(S): Mus musculus 
2009-08-27 | E-GEOD-15489 | biostudies-arrayexpress
UnknownBivalent intra-spike binding provides durability against emergent Omicron lineages: Results from a global consortium.
Not available
S-EPMC9834171 | biostudies-literature
UnknownPlasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study.
Not available
S-EPMC3419820 | biostudies-literature
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