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This experiment was designed to compare the transcriptome of a KO mutant of Bordetella pertussis (inactivation of bp2921,that we have called crpH) with that of the wt strain, BPSM. Because we observed that growth of the mutant was affected in low-aeration conditions, we grew wt and mutant bacteria w...
ORGANISM(S): Bordetella pertussis 
Alpibectir potentiates the activity of ethionamide and prothionamide, which are second-line antibiotics used for tuberculosis treatment. Both are prodrugs whose antibacterial activity depends on bioactivation by oxidases, including the Baeyer-Villiger monooxygenase MymA. Alpibectir binds the transcr...
ORGANISM(S): Mycobacterium tuberculosis 
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