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TranscriptomicsTranscriptional profiling of PRDM2 Knock down vs.controlGFPsh proliferating C2C12 Myoblasts
Knockdown of PRDM2 led to precocious differentiation. To understand the molecular basis for this phenotype, we performed microaary analysis of growing myoblasts. Genes differentially regulated by PRDM2 knock down were reveraled by microarray analysis using NIA15K mouse chips. Control and knock down...
ORGANISM(S): Mus musculus 
2015-06-30 | E-GEOD-58675 | biostudies-arrayexpress
TranscriptomicsTranscriptional profiling of PRDM2 Knock down vs.controlGFPsh Quiescent C2C12 Myoblasts (G0 enriched)
Knockdown of PRDM2 led to precocious differentiation. To understand the molecular basis for this phenotype, we performed microaary analysis of quiescent myoblasts. Genes differentially regulated by PRDM2 knock down were reveraled by microarray analysis using affymetrix mouse chips. Control and knoc...
ORGANISM(S): Mus musculus 
2015-06-30 | E-GEOD-58674 | biostudies-arrayexpress
TranscriptomicsTranscriptional profiling of PRDM2 Knock down vs.controlGFPsh differentiated C2C12 Myoblasts (D28hrs)
Knockdown of PRDM2 led to precocious differentiation. To understand the molecular basis for this phenotype, we performed microaary analysis of 28hr differentiated myoblasts. Genes differentially regulated by PRDM2 knock down were reveraled by microarray analysis using affymetrix mouse chips. Contro...
ORGANISM(S): Mus musculus 
2015-06-30 | E-GEOD-58673 | biostudies-arrayexpress
TranscriptomicsIdentification of targets genes of PRDM2 in G0 arrested myoblasts of C2C12
PRDM2 directly associates with the Myogenin promoter and repress its transcription. This led to the hypothesis that PRDM2 could potentially associate directly with other promoters and regulate their expression.To gain further insight into the pathways and genes controlled by PRDM2, ChIP-on-Chip anal...
ORGANISM(S): Mus musculus 
2015-06-30 | E-GEOD-58748 | biostudies-arrayexpress
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