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UnknownBlended Phenotype of Silver-Russell Syndrome and SPG50 Caused by Maternal Isodisomy of Chromosome 7.
Not available
S-EPMC7862086 | biostudies-literature
TranscriptomicsSRS endotype assignment of septic shock patients from the VANISH randomised trial
The aim of the experiment was to assign patients enrolled in the VANISH randomised trial to sepsis response signature (SRS) endotypes based on a previously published gene expression signature, in order to test for differential responses to treatment. VANISH was a double-blind randomised clinical tri...
ORGANISM(S): Homo sapiens 
2022-07-12 | E-MTAB-7581 | biostudies-arrayexpress
TranscriptomicsMethylation screening of reciprocal genome-wide UPDs identifies novel human specific imprinted genes
Utilizing reciprocal genome-wide uniparental disomy samples presenting with Beckwith-Wiedemann and Silver-Russell syndrome-like phenotypes, we have analyzed ~0.1% of CpG dinucleotides present in the human genome for imprinted differentially methylated regions (DMRs) using the Illumina Infinium Human...
ORGANISM(S): Homo sapiens 
2011-05-26 | E-GEOD-28525 | biostudies-arrayexpress
TranscriptomicsmiRNA alterations are an important mechanism in the adaptation of maize to a low-phosphate environment
Maize is a globally important food and feed crop, and a low-phosphate (Pi) supply in the soil frequently limits maize yield in many areas. MicroRNAs (miRNAs) play important roles in the development and adaptation of plants to the environment. In this study, the spatio-temporal miRNA transcript profi...
ORGANISM(S): Zea mays 
2015-07-08 | E-GEOD-70612 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse Dnmt3L+/- sires compared to offspring of Dnmt3L+/+ sires to investigate the effect of paternal haploinsufficiency for Dnmt3L
There is increasing evidence that epigenetic information can be inherited across generations in mammals, despite extensive reprogramming both in the gametes and the early developing embryo. One corollary to this is that disruption of the establishment of epigenetic state in the gametes of a parent, ...
ORGANISM(S): Mus musculus 
2008-06-15 | E-GEOD-7384 | biostudies-arrayexpress
TranscriptomicsMycobacterium tuberculosis Complex Clinical Isolates exhibit unique gene expression profiles in vitro and inside macrophages
This SuperSeries is composed of the following subset Series: GSE21111: Basal in vitro transcriptomes of Mycobacterium tuberculosis complex (MTC) clinical isolates GSE21112: Intracellular transcriptional adaptation of Mycobacterium tuberculosis complex (MTC) clinical isolates inside resting murine ma...
ORGANISM(S): Mycobacterium tuberculosis 
2010-07-09 | E-GEOD-21114 | biostudies-arrayexpress
TranscriptomicsRepliSeq of HT-1080 cell line
Analysis of replication timing by RepliSeq of HT-1080 Human Connective Tissue Fibrosarcoma Cells. HT-1080 subclone +4 cell line as described in “Human gene targeting favors insertions over deletions.” Russell, D.W., and Hirata, R.K. (2008). Hum Gene Ther 19, 907-914. RepliSeq of HT-1080 cell line w...
ORGANISM(S): Homo sapiens 
2014-07-31 | E-GEOD-58907 | biostudies-arrayexpress
UnknownAdvanced Hadamard-encoded editing of seven low-concentration brain metabolites: Principles of HERCULES.
Not available
S-EPMC6289748 | biostudies-literature
TranscriptomicsBasal in vitro transcriptomes of Mycobacterium tuberculosis complex (MTC) clinical isolates
This study uses microarray analyses to examine baseline gene expression profiles for Mycobacterium tuberculosis complex clinical isolates relative to reference strain CDC1551 during log phase growth in vitro in 7H9 broth. For this in vitro analyses, log-phase mycobacteria in starter cultures grown t...
ORGANISM(S): Mycobacterium tuberculosis 
2010-07-08 | E-GEOD-21111 | biostudies-arrayexpress
TranscriptomicsTranscriptional profiling of M. tuberculosis CDC1551 wild type vs aprABC null, aprBC null, aprC null and phoP transposon mutants.
Following phagocytosis by macrophages, Mycobacterium tuberculosis (Mtb) senses the intracellular environment and remodels its gene expression for growth in the phagosome. Abramovitch et.al. in this current study identified an Acid and Phagosome Regulated (aprABC) locus that is unique to the Mtb comp...
ORGANISM(S): Mycobacterium tuberculosis 
2011-07-09 | E-GEOD-22854 | biostudies-arrayexpress
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