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TranscriptomicsEsophageal keratinocyte invasion after loss of E-cadherin and TGF receptor type II
Esophageal cancer is one of the deadliest cancers as patients present at late stages of disease. Frequent gene alterations include the loss of E-cadherin and TGFb receptor type II. The goal of this study was to establish a model of esophageal cancer by introducing dominant-negative mutants of E-cadh...
ORGANISM(S): Homo sapiens 
2013-11-12 | E-GEOD-19472 | biostudies-arrayexpress
GenomicsWhole Genome and Exon Capture Sequencing of Bladder Cancers

One primary bladder cancer and paired peripheral blood sample were subjected to whole genome sequencing on an Illumina HiSeq 2000 platform. This technology was utilized to investigate the genetic basis of a durable remission of metastatic bladder cancer in a patient treated with everolimus, a dru...

phs000535.v1.p1 | EGA
TranscriptomicsDifferential expression of mouse Grem1+ Vs. Grem1- bone-marrow cells
The gene expression of bone marrow cells of mice enriched for Gremlin1 vs control was measured (n=3). It is not known if endogenous adult mesenchymal stem cells (MSCs) exist.Following culture,perisinusoidal mesenchymal cells can clonally recapitulate the skeletal microenvironment, but this fails to ...
ORGANISM(S): Mus musculus 
2015-02-10 | E-GEOD-57729 | biostudies-arrayexpress
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