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TranscriptomicsStress-related gene expression of HK-2 cells exposed to GF/FAF HSA, GF HSA, AngII or AngII+Cand
Proteinuria is pathogenic to proximal tubular cells (PTC) and linked with progression to renal failure. Angiotensin II (AngII) is also independently involved in the pathogenesis of progressive renal injury in varied kidney disease. The effects of human serum albumin (HSA) overload, AngII and candesa...
ORGANISM(S): Homo sapiens 
2010-06-25 | E-GEOD-10648 | biostudies-arrayexpress
TranscriptomicsStress-related gene expression in HK-2 cells exposed to pH 7.4, 7.0 or 6.7
Chronic metabolic acidosis occurs commonly in patients with diseased kidneys and is linked with progression to renal failure. As renal function declines there is loss of nephron mass and adaptive proximal tubular hypertrophy and hypermetabolism. We have previously demonstrated in an in vitro model o...
ORGANISM(S): Homo sapiens 
2012-09-11 | E-GEOD-23995 | biostudies-arrayexpress
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