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TranscriptomicsComparative genomic hybridization of plasmids containing genomic library clones grown in E. coli to monitor copy number changes over time
We report a genome-wide, multi-scale approach to simultaneously measure the effect that the increased copy of each gene and/or operon has on a desired trait or phenotype. The method involves i) growth selections on a mixture of several different plasmid based genomic libraries of defined insert size...
ORGANISM(S): Escherichia coli 
2006-10-26 | E-TABM-143 | biostudies-arrayexpress
Unknownp63 silencing induces epigenetic modulation to enhance human cardiac fibroblast to cardiomyocyte-like differentiation.
Not available
S-EPMC9259667 | biostudies-literature
UnknownPhase IB Study of Selinexor, a First-in-Class Inhibitor of Nuclear Export, in Patients With Advanced Refractory Bone or Soft Tissue Sarcoma.
Not available
S-EPMC5321073 | biostudies-literature
UnknownTransverse tendon stiffness is reduced in people with Achilles tendinopathy: A cross-sectional study.
Not available
S-EPMC6382130 | biostudies-literature
UnknownCapecitabine and oxaliplatin in the preoperative multimodality treatment of rectal cancer: surgical end points from National Surgical Adjuvant Breast and Bowel Project trial R-04.
Not available
S-EPMC4050205 | biostudies-literature
TranscriptomicsMicroarray expression data from human renal mesangial cells (HMC) treated with a Cyclosporine A (CsA) time course.
HMCs were treated with CsA (4.2 M-BM-5M) for 0 12 and 48 hours. To exmaine global gene changes in the renal mesangium following CsA treatment in order to identify novel contributors to CsA-induced renal dysfunction Microarray analysis was used to identify novel mechanisms of CsA nephrotoxicity in th...
ORGANISM(S): Homo sapiens 
2012-04-03 | E-GEOD-30952 | biostudies-arrayexpress
TranscriptomicsInhibitory Actions of Anti-MM-CM-
The current study was designed to investigate the actions of Anti-MM-CM-
ORGANISM(S): Rattus norvegicus 
2011-03-04 | E-GEOD-25629 | biostudies-arrayexpress
Genomics
Tumor-infiltrating lymphocytes RNASeq
PRJNA1120915 | ENA
GenomicsGenome-wide CRISPR-Cas9 knockout screen in MCF10A with ATP-competitive inhibition of CDC7 (XL-413)
The coordinated activation of DNA replication origins is important for efficient DNA synthesis and genome stability. S-phase cyclin dependent kinases (CDKs) together with CDC7 kinase, are essential to origin activation by converting the pre-replicative complex into a fully active helicase. To identi...
ORGANISM(S): Homo sapiens 
2026-09-30 | E-MTAB-17434 | biostudies-arrayexpress
UnknownFibroblast transition to an endothelial "trans" state improves cell reprogramming efficiency.
Not available
S-EPMC8604927 | biostudies-literature
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