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TranscriptomicsTranscription profiling of zebrafish livers following exposure to 17 alpha-ethynylestradiol (EE2) at 0, 15, 40, or 100 ng/L
Genomic, proteomic, and metabolomic technologies continue to receive increasing interest from environmental toxicologists. This interest is due to the great potential of these technologies to identify detailed modes of action and to provide assistance in the evaluation of a contaminant?s risk to aq...
ORGANISM(S): Danio rerio 
2007-02-24 | E-TABM-105 | biostudies-arrayexpress
TranscriptomicsComparative Genomic Analysis of PhoP Regulon in S. Typhi and S. Typhimurium
Transcriptional profiling of three sequenced S. enterica strains: S. Typhimurium LT2, S. Typhi CT18, and S. Typhi Ty2 in PhoP-inducing and non-inducing conditions in vitro, and compared these results to profiles of phoP-/Q- mutants derived from S. Typhimurium LT2 and S. Typhi Ty2. Two-condition expe...
ORGANISM(S): Salmonella enterica subsp. enterica serovar Typhimurium str. LT2 
2010-05-06 | E-GEOD-17670 | biostudies-arrayexpress
GenomicsHDAC-regulated myomiRs control BAF60 variant exchange and direct the functional phenotype of fibroadipogenic progenitors in dystrophic muscles
Fibro-adipogenic progenitors (FAPs) are emerging cellular components of the skeletal muscle regenerative environment. The alternative functional phenotype of FAPs - either supportive of muscle regeneration or promoting fibro-adipogenic degeneration M-bM-^@M-^S is a key determinant in the pathogenesi...
ORGANISM(S): Mus musculus 
2014-04-02 | E-GEOD-52062 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of C. elegans larvae hatching in the presence and absence of food, time series
When C. elegans larvae hatch in the absence of food they persist in a stress resistant, developmentally arrested state (L1 arrest). We characterized mRNA expression genome-wide in a pair of bifurcating time series starting in the late embryo and proceeding through the hatch in the presence and abse...
ORGANISM(S): Caenorhabditis elegans 
2009-03-07 | E-GEOD-11055 | biostudies-arrayexpress
TranscriptomicsOrigin-Dependent DNA Replication in vitro: Insights into DDK and S-CDK function and Replisome Assembly
Initiation of eukaryotic DNA replication requires temporal separation of helicase loading from helicase activation and replisome assembly. Using an in vitro assay for eukaryotic origin-dependent replication initiation, we investigated the control of these events. After helicase loading, we found t...
ORGANISM(S): Saccharomyces cerevisiae 
2011-07-21 | E-GEOD-29646 | biostudies-arrayexpress
GenomicsWhole-genome nucleosome mapping in meiotic diploid S. cerevisiae
We determined nucleosome positions throughout the genome in diploid S. cerevisiae undergoing early stages of synchronous meiosis. This study sought to assess if systematic reorganization of nucleosomes occurs during meiotic prophase at or near sites of DNA double strand break formation. Six samples ...
ORGANISM(S): Saccharomyces cerevisiae 
2011-03-07 | E-GEOD-26452 | biostudies-arrayexpress
TranscriptomicsAbscisic Acid Transcriptomic Signaling Varies with Grapevine Organ
Background: Abscisic acid (ABA) regulates various developmental processes and stress responses over both short (i.e. hours or days) and longer (i.e. months or seasons) time frames. To elucidate the transcriptional regulation of early responses of grapevine (Vitis vinifera) responding to ABA, differe...
ORGANISM(S): Vitis vinifera 
2016-03-01 | E-GEOD-78798 | biostudies-arrayexpress
TranscriptomicsGene expression profile of an ldhA-pflB- double knockout strain of E. coli BW25113 relative to wild-type
Comparison of gene expression profile in E. coli BW25113 wild type and ldhA-pflB- double mutant growing microaerobically in M9 media containing 10 g/L Glucose two samples: wild type and mutant
ORGANISM(S): Escherichia coli 
2010-06-08 | E-GEOD-21995 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Helicobacter pylori bearing FliK mutation to investigate the effect of the mutation on expression of eI?54 sigma factor RpoN in Helicobacter pylori
Data is also available from http://bugs.sgul.ac.uk/E-BUGS-78
ORGANISM(S): Helicobacter pylori 
2009-04-28 | E-BUGS-78 | biostudies-arrayexpress
UnknownRadiographic progression-free survival as a response biomarker in metastatic castration-resistant prostate cancer: COU-AA-302 results.
Not available
S-EPMC4881370 | biostudies-literature
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