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MetabolomicsTo explore the role of circulating oxidized lipids in the progression and prognosis of SA-AKI by means of histochemistry

Background: Plasma oxidized lipids are intimately linked to immune regulation as bioactive mediators. However, it is not clear whether they are related to the progression of sepsis-associated acute kidney injury (SA-AKI) and the effect of continuous renal replacement therapy (CRR...

2024-12-16 | MTBLS11695 | MetaboLights
MetabolomicsThe glycosyltransferase UGT76B1 modulates N-hydroxy-pipecolic acid homeostasis and plant immunity
The trade-off between growth and defense is a critical aspect of plant immunity. Therefore, the plant immune response needs to be tightly regulated. Salicylic acid (SA) is an important plant hormone regulating defense against biotrophic pathogens. Recently, N-hydroxy-pipecolic acid (NHP) was identif...
2022-02-28 | MTBLS2334 | MetaboLights
TranscriptomicsArabidopsis CBP60g Contributes to MAMP-Induced SA Accumulation and Is Involved in Disease Resistance
Salicylic acid (SA)-induced defense responses are important factors during effector triggered immunity and microbe-associated molecular pattern (MAMP)-induced immunity in plants. This article presents evidence that a member of the Arabidopsis CBP60 gene family, CBP60g, contributes to MAMP-triggered ...
ORGANISM(S): Arabidopsis thaliana 
2010-05-07 | E-GEOD-14237 | biostudies-arrayexpress
TranscriptomicsNicotinamide N-Methyltransferase drives fibroblast activation and skin fibrosis in systemic sclerosis
Systemic sclerosis (SSc) is characterized by progressive skin and organ fibrosis driven by persistently activated fibroblasts, however, the mechanisms of dermal fibroblast (DF) activation remain unclear. Nicotinamide N-methyltransferase (NNMT) has been linked to fibrosis in other diseases, but its r...
ORGANISM(S): Homo sapiens 
2026-10-20 | E-MTAB-17206 | biostudies-arrayexpress
TranscriptomicsNicotinamide N-Methyltransferase drives fibroblast activation and skin fibrosis in systemic sclerosis
Systemic sclerosis (SSc) is characterized by progressive skin and organ fibrosis driven by persistently activated fibroblasts, however, the mechanisms of dermal fibroblast (DF) activation remain unclear. Nicotinamide N-methyltransferase (NNMT) has been linked to fibrosis in other diseases, but its r...
ORGANISM(S): Homo sapiens 
2026-10-20 | E-MTAB-17207 | biostudies-arrayexpress
TranscriptomicsTranscriptional response of Arabidopsis thaliana to exogenous application of N-hydroxypipecolic acid (NHP).
Previous studies from our laboratory have shown that the resistance increase observed after biological systemic acquired resistance (SAR) induction in plants can be mimicked by exogenous plant treatment with N-hydroxypipecolic acid (NHP, Hartmann et al., 2018, Schnake et al., 2020). Moreover, exoge...
ORGANISM(S): Arabidopsis thaliana 
2021-05-03 | E-MTAB-10230 | biostudies-arrayexpress
ProteomicsN-Glycoproteomic Analysis of Botryococcus Braunii
We have performed an N-glycoproteomic analysis of the green microalgae Botryococcus braunii, a promising candidate for the production of biofuels, accumulating considerable amounts of hydrocarbon oils. Thereby, three different strains have been compared: Showa (Race B), AC761 (Race B) and CCALA778 (...
ORGANISM(S): Botryococcus braunii 
2017-08-08 | PXD005708 | Pride
Algae Botryococcus braunii N-glycosylation 
ModelsIrani2015 - Genome-scale metabolic model of P.pastoris N-glycosylation
Irani2015 - Genome-scale metabolic model of P.pastoris N-glycosylation This model is described in the article: Genome-scale metabolic model of Pichia pastoris with native and humanized glycosylation of recombinant proteins. Irani ZA, Kerkhoven E, Shojaosadati SA, Nielsen J. ...
2024-10-15 | BIOMD0000001096 | BioModels
FROG 
GenomicsEarly N-hydroxy-pipecolic acid transcriptional profile
Early N-hydroxy-pipecolic acid transcriptional profile
PRJNA1096619 | ENA
TranscriptomicsDifferent gene expression profile in acute coronary sindrome (ACS) patients compared to stable angina(SA) patients.
We have employed whole genome microarray expression profiling as a discovery platform to identify genes involved in plaque rupture. Human coronary artery endothelial cells (ECs) were stimulated in vitro for 12 hours with plasma obtained from the coronary sinus (CS) and the aorta (Ao) of patients wit...
ORGANISM(S): Homo sapiens 
2014-02-14 | E-GEOD-54977 | biostudies-arrayexpress
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