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TranscriptomicsIn vivo gene expression in granulosa cells during pig terminal follicular development.
The aim of this study is the identification of genes and gene networks involved in pig ovarian follicular development. cDNA nylon micro-arrays (2849 sequenced clones) were designed from different libraries : four subtractive suppressive hybridization libraries (generated from small versus large and ...
ORGANISM(S): Sus scrofa 
2008-04-30 | E-GEOD-5798 | biostudies-arrayexpress
TranscriptomicsIn vivo gene expression in granulosa cells during pig terminal follicular development- oligo
These vector oligonucleotide hybridizations were performed to determine the quality of the spotting process. EST with low signal values of the vector array were excluded from the analysis, since they probably were mis-amplified or mis-spotted Keywords: spotting control cDNA arrays (GPL3978) were fi...
ORGANISM(S): Sus scrofa 
2008-04-30 | E-GEOD-5797 | biostudies-arrayexpress
TranscriptomicsIntegrated molecular pathway analysis informs a synergistic combination therapy targeting PTEN/PI3K and EGFR pathways for basal-like breast cancer.
Abstract BACKGROUND: The basal-like breast cancer (BLBC) subtype is characterized by positive staining for basal mammary epithelial cytokeratin markers, lack of hormone receptor and HER2 expression, and poor prognosis with currently no approved molecularly-targeted therapies. The oncogenic signaling...
ORGANISM(S): Homo sapiens 
2016-08-21 | E-GEOD-74667 | biostudies-arrayexpress
TranscriptomicsThe retinoblastoma gene is targeted for rearrangements in BRCA1-deficient basal-like breast cancer.
Breast tumors from BRCA1 germ line mutation carriers typically exhibit features of the basal-like molecular subtype. However, the specific genes recurrently mutated as a consequence of BRCA1 dysfunction have not been fully elucidated. In this study, we utilized gene expression profiling to molecular...
ORGANISM(S): Homo sapiens 
2012-06-26 | E-GEOD-25307 | biostudies-arrayexpress
UnknownMolecular and genetic diversity in the metastatic process of melanoma.
Not available
S-EPMC4359751 | biostudies-literature
UnknownPoor prognosis in carcinoma is associated with a gene expression signature of aberrant PTEN tumor suppressor pathway activity.
Not available
S-EPMC1855070 | biostudies-literature
UnknownIntegrated molecular pathway analysis informs a synergistic combination therapy targeting PTEN/PI3K and EGFR pathways for basal-like breast cancer.
Not available
S-EPMC4971667 | biostudies-literature
UnknownSerial monitoring of circulating tumor DNA in patients with primary breast cancer for detection of occult metastatic disease.
Not available
S-EPMC4551342 | biostudies-literature
ProteomicsProteomic and phosphoproteomic analysis of ESR1 mutant cells
Three quarters of all breast cancer cases express the estrogen receptor (ER, ESR1 gene), which promotes tumor growth and constitutes a direct target for endocrine therapies. ESR1 mutations have been implicated in therapy resistance in metastatic breast cancers, in particular to aromatase inhibitors....
ORGANISM(S): Homo sapiens (Human) 
2024-03-26 | PXD046446 | Pride
Breast cancer Human 
UnknownMolecular stratification of metastatic melanoma using gene expression profiling: Prediction of survival outcome and benefit from molecular targeted therapy.
Not available
S-EPMC4494939 | biostudies-literature
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