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TranscriptomicsAcute and long-term effects of mutant p53 in vivo [MEF]
The specific roles of mutant p53’s dominant-negative (DN) or gain-of-function (GOF) properties in regulating acute response and long-term tumorigenesis is unclear. Using “knock-in” mouse strains expressing varying R246S mutant levels, we show that DN effect on transactivation is universally observ...
ORGANISM(S): Mus musculus 
2012-12-31 | E-GEOD-40416 | biostudies-arrayexpress
TranscriptomicsAcute and long-term effects of mutant p53 in vivo
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Mus musculus 
2012-12-31 | E-GEOD-40417 | biostudies-arrayexpress
TranscriptomicsAcute and long-term effects of mutant p53 in vivo [B cells]
The specific roles of mutant p53’s dominant-negative (DN) or gain-of-function (GOF) properties in regulating acute response and long-term tumorigenesis is unclear. Using “knock-in” mouse strains expressing varying R246S mutant levels, we show that DN effect on transactivation is universally observ...
ORGANISM(S): Mus musculus 
2012-12-31 | E-GEOD-40415 | biostudies-arrayexpress
TranscriptomicsAcute and long-term effects of mutant p53 in vivo [Thymus]
The specific roles of mutant p53’s dominant-negative (DN) or gain-of-function (GOF) properties in regulating acute response and long-term tumorigenesis is unclear. Using “knock-in” mouse strains expressing varying R246S mutant levels, we show that DN effect on transactivation is universally observ...
ORGANISM(S): Mus musculus 
2012-12-31 | E-GEOD-40414 | biostudies-arrayexpress
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