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ProteomicsRegulatory impact of a 5’UTR resident Single Nucleotide Variant on EDN1 gene expression and RNA-protein interactions
Non-coding regulatory variants are gaining a lot of attention in recent years. This study identifies a 5’UTR variant of the Endothelin-1 gene (EDN1) linked to elevated production of Endothelin-1. The potent vasoactive Endothelin-1 (ET-1) peptide is implicated in vascular homeostasis. Its dysregulate...
ORGANISM(S): Homo sapiens (Human) 
2026-06-01 | PXD076288 | Pride
Et-1: endothelin-1  edn1: endothelin-1 gene  cad: coronary artery disease  snps/snvs: single nucleotide polymorphisms/single nucleotide variants  5′utr: 5′untranslated region  ins./del.: insertion/deletion  hek293t: human embryonic kidney (293-t) cells  huvec: human umbilical vein endothelial cells  dhx9: dexh-box helicase 9  hnrpa3: heterogeneous nuclear ribonucleoprotein a3 
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