Mass spectrometry was used to determine that cellular IQGAP1 and IQGAP2 proteins are phosphorylated at multiple tyrosine residues upon sodium orthovanadate treatment.
Mass spectrometry was used to determine IQGAP1 is a substrate of MET and c-Src, and is phosphorylated exclusively on Tyr-1510 under conditions with enhanced MET or c-Src cellular activity.
