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ProteomicsProteomic analysis of mitochondrial biogenesis in cardiomyocytes differentiated from human induced pluripotent stem cell
Mitochondria play a crucial role in the differentiation and maturation of human cardiomyocytes (CMs). To identify mitochondrial pathways and regulators that are involved in cardiac differentiation and maturation, we examined human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs). Pro...
ORGANISM(S): Mus musculus (Mouse) Homo sapiens (Human) 
2022-05-19 | PXD014317 | Pride
Human induced pluripotent stem cells Proteomics Canonical pathways Upstream regulator. Mitochondria Cardiac differentiation 
ProteomicsMultiomic analysis of PI3K in Atrial Myopathy
Here, we undertook comprehensive physiological and molecular analyses in cardiac-specific transgenic mice with increased or decreased PI3K to assess the dose response impact of directly regulating PI3K. Elevated PI3K was associated with a dose-dependent increase in heart size, and preserved/enhanced...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
MSV000092855 | MassIVE
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