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TranscriptomicsNuclear Matrix Factor hnRNP U/SAF-A Exerts a Global Control of Alternative Splicing by Regulating U2 snRNP Maturation
The nuclear matrix associated hnRNP U/SAF-A protein has been implicated in diverse pathways from transcriptional regulation to telomere length control to X inactivation, but the precise mechanism underlying each of these processes has remained elusive. Here, we report hnRNP U as a regulator of SM...
ORGANISM(S): Homo sapiens 
2012-02-16 | E-GEOD-34491 | biostudies-arrayexpress
GenomicsSingle-cell replication timing analysis of hTERT-RPE1 cells depleted for SAF-A protein
The impact of depleting SAF-A (HNRNPU) on the genome-wide replication timing program in human hTERT-RPE1 cells was assessed by a single-cell replication timing analysis.
ORGANISM(S): Homo sapiens 
2021-12-15 | E-MTAB-10234 | biostudies-arrayexpress
GenomicsStaphylococcus aureus strain:SAF
Characterisation of a CC-15 S. aureus strain colonising mice
PRJNA299876 | ENA
GenomicsJPL SAF Metagenome
JPL SAF Metagenome Raw sequence reads
PRJNA641034 | ENA
GenomicsSAF PP Metagenome
SAF PP Metagenome Raw sequence reads
PRJNA668809 | ENA
GenomicsRole of the SAF-A SAP domain in X inactivation, transcription, splicing, and cell proliferation [CutandRun]
Role of the SAF-A SAP domain in X inactivation, transcription, splicing, and cell proliferation [CutandRun]
PRJNA1161386 | ENA
GenomicsRole of the SAF-A ATPase and RGG domains in X inactivation, transcription, splicing, and cell proliferation.
Role of the SAF-A ATPase and RGG domains in X inactivation, transcription, splicing, and cell proliferation.
PRJNA1363567 | ENA
GenomicsRole of the SAF-A SAP domain in X inactivation, transcription, splicing, and cell proliferation [ATAC-seq]
Role of the SAF-A SAP domain in X inactivation, transcription, splicing, and cell proliferation [ATAC-seq]
PRJNA1161378 | ENA
GenomicsRole of the SAF-A SAP domain in X inactivation, transcription, splicing, and cell proliferation [RNA-seq]
Role of the SAF-A SAP domain in X inactivation, transcription, splicing, and cell proliferation [RNA-seq]
PRJNA1161384 | ENA
OtherChromatin associated α-satellite RNA maintains chromosome stability by re-establishing SAF-A in the mitotic cell cycle [ChIRP-seq]
RNA components seem to be required for the localization of SAF-A on chromatin. A SAF-A/RNA mesh model has been proposed and supported by super-resolved images, in which SAF-A forms a homogeneous mesh together with nuclear scaffolding RNA species to regulate chromatin structure. As an evolutionarily ...
ORGANISM(S): Homo sapiens 
2025-03-25 | GSE270307 | GEO
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