Sort   by:  
 Page size 
TranscriptomicsEpigenome analysis of buccal cells from monozygotic and dizygotic twins
Using the Infinium HM450 platform, we have performed a longitudinal study of DNA methylation at birth and age 18 months in DNA from buccal swabs from 10 monozygotic (MZ) and 5 dizygotic (DZ) twin pairs from the Peri/postnatal Epigenetic Twins Study (PETS) cohort. Beta methylation measurements from b...
ORGANISM(S): Homo sapiens 
2013-03-06 | E-GEOD-42700 | biostudies-arrayexpress
TranscriptomicsNeonatal DNA methylation profile in humans is specified by a complex interplay between intrauterine environmental/ genetic factors subject to tissue-specific influence
Comparison between groups of monozygotic (MZ) and dizygotic (DZ) twins enables an estimation of the relative contribution of genetic, shared and non-shared environmental factors to phenotypic variability. Using DNA methylation profiling of ~20,000 CpG sites as a phenotype, we have examined discordan...
ORGANISM(S): Homo sapiens 
2012-07-17 | E-GEOD-36642 | biostudies-arrayexpress
ProteomicsSIRT1 binding proteins in human first trimester villi and HTR8/SVneo cells
In this study, we investigated the potential downstream target proteins in trophoblasts that were regulated by SIRT1 through modulation of acetylation. To this end, the IP products of SIRT1 in the lysate of human first-trimester villous tissue and HTR8/SVneo cells were subjected to proteomics analys...
ORGANISM(S): Homo Sapiens 
2021-06-08 | PXD026574 |
TranscriptomicsWide ranging DNA methylation differences of primary trophoblast cell populations and derived-cell lines
Difficulties associated with long term culture of primary trophoblasts have proven to be a major hurdle in their functional characterization. In order to circumvent this issue, several model cell lines have been established over many years using a variety of different approaches. Due to their differ...
ORGANISM(S): Homo sapiens 
2011-01-20 | E-GEOD-26683 | biostudies-arrayexpress
Sort   by:  
 Page size