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TranscriptomicsRecruitment of FOXP1 to target genes in diffuse large B-cell lymphoma (DLBCL) cells
Identification of FOXP1 target genes in the OCI-Ly1 DLBCL cell line by ChIP-on-chip Three replicates of the FOXP1 ChIP-on-chip were performed in the OCI-Ly1 cells
ORGANISM(S): Homo sapiens 
2013-05-03 | E-GEOD-44243 | biostudies-arrayexpress
TranscriptomicsA Novel Pro-Survival Function of Cyclin-D1 Underlies Its Oncogenic Role and Potential as a Therapeutic Target in Human and Murine Mantle Cell Lymphoma
The chromosomal translocation t(11;14)(q13;q32) leading to cyclin-D1 over-expression plays an essential role in the development of mantle cell lymphoma (MCL), an aggressive tumor that remains incurable with current therapies. Cyclin-D1 has been postulated as an effective therapeutic target, but it...
ORGANISM(S): Homo sapiens 
2011-07-01 | E-GEOD-25613 | biostudies-arrayexpress
TranscriptomicsGlobal expression analysis of DLBCL cell lines with LITAF over-expression or silencing
The multifunctional protein lipopolysaccharide-induced TNFalpha factor (LITAF) induces the secretion of inflammatory cytokines in monocytes and regulates protein degradation in neural cells. In B-cell lymphomas, LITAF is frequently inactivated by epigenetic mechanisms, but beyond these data little i...
ORGANISM(S): Homo sapiens 
2012-11-10 | E-GEOD-42174 | biostudies-arrayexpress
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