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TranscriptomicsTranscriptomic analysis of human breast and prostate cancer cell lines on lysophosphatidic acid (LPA) stimulation
LPA is a natural bioactive lipid with growth factor-like functions due to activation of series of six G protein-coupled receptors (LPA1-6). In this study we determine the LPA induced early-gene expression profile in three unrelated human cancer cell lines (MDA-MB-231, MCF7, PC3) with an objective to...
ORGANISM(S): Homo sapiens 
2014-05-16 | E-GEOD-56265 | biostudies-arrayexpress
UnknownEstablishing Objective Measures of Clinical Competence in Undergraduate Medical Education Through Immersive Virtual Reality.
Not available
S-EPMC7572369 | biostudies-literature
UnknownImproved localized mRNA delivery using lipid nanoparticles with a novel synthetic cholesterol derivative.
Not available
S-EPMC12606572 | biostudies-literature
UnknownEngineered mutant α-ENaC subunit mRNA delivered by lipid nanoparticles reduces amiloride currents in cystic fibrosis-based cell and mice models.
Not available
S-EPMC7673816 | biostudies-literature
UnknownEffects of Semaglutide With or Without Concomitant Mineralocorticoid Receptor Antagonist Use in Participants With Type 2 Diabetes and Chronic Kidney Disease: A FLOW Trial Prespecified Secondary Analysis.
Not available
S-EPMC12583412 | biostudies-literature
UnknownIlluminating endosomal escape of polymorphic lipid nanoparticles that boost mRNA delivery.
Not available
S-EPMC8769212 | biostudies-literature
UnknownDomestic violence against women in India: A systematic review of a decade of quantitative studies.
Not available
S-EPMC4988937 | biostudies-literature
ProteomicsLNP formulations for efficient hepatic delivery studied with an in-vivo endosomal escape assay
Endosomal escape is a central barrier to efficient nucleic acid delivery by lipid nanoparticles (LNPs) and remains challenging to quantify in vivo. We report a library of branched ionizable phospholipids (BiPs) that markedly enhance mRNA delivery to the liver. The lead candidate BiP-20 outperformed ...
ORGANISM(S): Mus musculus (Mouse) 
2026-01-20 | PXD072066 | Pride
Lipid nanoparticle Mass spectrometry Endosomal escape Quantitative proteomics Gene editing 
UnknownLipid nanoparticles for delivery of messenger RNA to the back of the eye.
Not available
S-EPMC6579630 | biostudies-literature
UnknownLipid nanoparticles with PEG-variant surface modifications mediate genome editing in the mouse retina.
Not available
S-EPMC10575971 | biostudies-literature
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