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ProteomicsPlasma Proteomics Reveal COVID-19 Associated Network and Severity Biomarkers
Coronavirus disease 2019 (COVID-19) has been threatening public health for the last 3 years globally. So far, the pathophysiology of the disease and therapeutic strategies have not clearly known yet. In this project, performing label-free plasma proteomics analysis, we aimed at identifying severity ...
ORGANISM(S): Severe acute respiratory syndrome coronavirus 2 Homo sapiens (Human) 
2023-03-11 | PXD031813 | Pride
Severity biomarkers Covid-19 associated network Label-free quantification Covid-19 disease Mass-spectrometry based plasma proteomics 
ProteomicsQuantitative proteomics identifies secreted diagnostic biomarkers as well as tumor-dependent prognostic targets for clear cell Renal Cell Carcinoma
Clear cell Renal Cell Carcinoma (ccRCC) is the third most common and most malignant urological cancer, with a 5-year survival rate of 10% for patients with advanced tumors. Here, we identified 10,160 unique proteins by in-depth quantitative proteomics, of which 955 proteins were significantly regula...
ORGANISM(S): Homo sapiens (Human) 
2021-11-02 | PXD024696 | Pride
Proteomics Urine Biomarkers Renal cell carcinoma Drug repurposing 
ProteomicsQuantitative phosphoproteomics analysis uncovers CDK1- and PAK2-mediated malignant signaling pathways in clear cell Renal Cell Carcinoma
Clear cell Renal Cell Carcinoma (ccRCC) is among the 10 most common cancers and causes more than 140,000 deaths worldwide every year. In order to elucidate the underlying molecular mechanisms orchestrated by phosphorylation modifications, we performed a comprehensive quantitative phosphoproteomics c...
ORGANISM(S): Homo sapiens (Human) 
2023-03-10 | PXD028428 | Pride
Biomarkers Signaling pathways Drug targets Phosphoproteomics Renal cell carcinoma 
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