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ProteomicsHistone Modification Analysis of Oligodendroglioma and Astrocytoma Brain Cancer Samples
WHO classification for tumors of the central nervous system strongly endorses molecular tests for the precise diagnosis of diffuse gliomas. While alterations in the DNA methylation status of gliomas are already well documented and used in specialised clinical centers to distinguish between brain tum...
ORGANISM(S): Homo sapiens (Human) 
2020-01-17 | PXD015151 | Pride
Oligodendroglioma Histone modifications Brain cancer Astrocytoma Histone epi-proteome 
ProteomicsProteomic characterization of cerebrospinal fluid in patients with brain malignancies
Recent technological advances in molecular diagnostics through liquid biopsies hold the promise to monitor tumor evolution and treatment response of brain malignancies without the need of invasive surgical tissue accrual. Here, we implemented a new mass spectrometry-based protein analysis pipeline a...
ORGANISM(S): Homo sapiens (Human) 
2021-03-25 | PXD021984 | Pride
Brain tumor Glioblastoma Proteome Biomarker 
Genomicsena-DATASET-DKFZ-IBIOS-01-08-2014-08:50:46:817-29 - samples
Low-coverage whole genome sequencing of sporadic schwannomatosis patients
EGAD00001000964 | EGA
Genomicsena-DATASET-DKFZ-IBIOS-01-08-2014-08:47:40:399-28 - samples
Exome sequencing of sporadic schwannomatosis patients
EGAD00001000963 | EGA
GenomicsNext generation sequencing of sporadic schwannomatosis samples
Schwannomatosis (MIM #162091) is characterized by the development of multiple schwannomas without vestibular nerve involvement (which is a characteristic of neurofibromatosis type 2 - NF2). In an effort to detect novel genetic alterations predisposing to schwannomatosis, we sequenced eight tumor-blo...
EGAS00001000767 | EGA
Genomicsbe40ebac-acee-4026-a661-4330bb0f657b - samples
Bam files for 124 samples (62 tumor vs blood pairs); Whole Genome Sequencing performed on Illumina HiSeq X Ten
EGAD00001005061 | EGA
Genomicsbc246e56-19ea-4c30-9e33-160ac12c3050 - samples
Bam files for 16 meningioma tumor samples; ChIPseq performed on Illumina HiSeq 2000
EGAD00001005021 | EGA
GenomicsMutational patterns and regulatory networks in epigenetic subgroups of meningioma (H033)
DNA methylation patterns delineate clinically relevant subgroups of meningioma. We previously established the six meningioma methylation classes (MC) benign-1, 2, 3, intermediate-A, B and malignant. Here, we set out to identify subgroup-specific mutational patterns and pathway regulation. Whole-gen...
EGAS00001003481 | EGA
GenomicsData Access Committee of divisions B060 and B062, German Cancer Research Center (DKFZ)
Data Access Committee EGAC00001000219
EGAC00001000219 | EGA
UnknownOligosarcomas, IDH-mutant are distinct and aggressive.
Not available
S-EPMC8742817 | biostudies-literature
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