Sort   by:  
 Page size 
TranscriptomicsEffect of TTF-1/NKX2-1 expression on TGF-beta induced gene expression in A549 lung cancer cell line.
TTF-1/NKX2-1 was expressed by adenoviral vector and changes in gene expression were determined by RNA-sequencing. A549 cells were infected with Ad-TTF-1 or Ad-LacZ vectors and stimulated with TGF-beta for 24 hours or left untreated. Expression of polyA RNA was determined.
ORGANISM(S): Homo sapiens 
2014-07-27 | E-GEOD-56356 | biostudies-arrayexpress
TranscriptomicsExpression data of human lung adenocarcinoma cell line H441 treated with TTF-1/NKX2-1 siRNA and TGF-beta
We determined and analyzed the effect of TTF-1/NKX2-1 on Smad3/Smad4 binding sites by ChIP-sequencing. We used expression microarrays to evaluate the effect of TTF-1/NKX2-1 siRNA on TGF-beta-induced gene expressions. H441 cells were transfected with siRNAs and treated with TGF-beta for RNA extractio...
ORGANISM(S): Homo sapiens 
2014-07-27 | E-GEOD-49675 | biostudies-arrayexpress
GenomicsSmad3, Smad4 and TTF-1/NKX2-1 binding sites in H441/A549 lung cancer cell lines
We evaluated the role of TTF-1/NKX2-1 on Smad3 and Smad4 binding in lung cancer cell lines. Smad3 binding sites in A549 cells and Smad3, Smad4, and TTF-1/NKX2-1 binding sites in H441 cells were determined by ChIP-seq.
ORGANISM(S): Homo sapiens 
2014-07-27 | E-GEOD-51509 | biostudies-arrayexpress
TranscriptomicsGenes regulated by TAZ in lung cancer cell lines
To investigate the roles of TAZ in lung cancer cell proliferation, we compared the expression profiles of A549 and H441 lung adenocarcinoma cell lines transfected with control siRNA and siTAZ. We collected RNA from A549 and H441 cell lines transfected with control siRNA and siTAZ.
ORGANISM(S): Homo sapiens 
2014-06-25 | E-GEOD-51270 | biostudies-arrayexpress
TranscriptomicsMicroarray analysis of an RXR agonist HX630 regulated gene expression in murine pituitary corticotroph tumor cells (AtT20 cell)
To gain insight into the functional mechanisms of an RXR agonist HX630 in murine pituitary corticotroph tumor cells (AtT20 cell), especially concerning cell proliferation and apoptosis, we conducted whole genome microarray analysis to identify gene expression patterns, networks, and pathways in AtT2...
ORGANISM(S): Mus musculus 
2013-01-27 | E-GEOD-43783 | biostudies-arrayexpress
UnknownRAE1 ligands for the NKG2D receptor are regulated by STING-dependent DNA sensor pathways in lymphoma.
Not available
S-EPMC4229084 | biostudies-literature
UnknownRegulation of innate antiviral defenses through a shared repressor domain in RIG-I and LGP2.
Not available
S-EPMC1766428 | biostudies-literature
TranscriptomicsDifferentially expressed genes among motor and prefrontal areas of macaque monkey neocortex
Motor-related areas of neocortex are highly differentiated into several subareas from both functional and cytoarchitectural aspects in the higher primates. To assess the molecular basis of such areal specialization, we investigated the gene expression profiles of primary motor area (M1), premotor ar...
ORGANISM(S): Macaca mulatta 
2007-08-31 | E-GEOD-8644 | biostudies-arrayexpress
TranscriptomicsModeling the early phenotype at the neuromuscular junction of spinal muscular atrophy using patient-derived iPSCs (RNA-Seq)
Spinal muscular atrophy (SMA) is a neuromuscular disorder caused by mutations of the survival of motor neuron 1 (SMN1) gene. In the pathogenesis of SMA, pathological changes of the neuromuscular junction (NMJ) precede the motor neuronal loss. Therefore, it is critical to evaluate the NMJ formed by S...
ORGANISM(S): Homo sapiens 
2015-02-03 | E-GEOD-65508 | biostudies-arrayexpress
TranscriptomicsModeling the early phenotype at the neuromuscular junction of spinal muscular atrophy using patient-derived iPSCs
Spinal muscular atrophy (SMA) is a neuromuscular disorder caused by mutations of the survival of motor neuron 1 (SMN1) gene. In the pathogenesis of SMA, pathological changes of the neuromuscular junction (NMJ) precede the motor neuronal loss. Therefore, it is critical to evaluate the NMJ formed by S...
ORGANISM(S): Homo sapiens 
2015-01-31 | E-GEOD-65470 | biostudies-arrayexpress
Sort   by:  
 Page size