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TranscriptomicsNickel Chloride (NiCl2) effect on human T cells from whole blood
Analysis of anti-CD3/anti-CD28 stimulated T cells treated with or without nickel chloride. Nickel is the most important contact allergen in the general population of the industrialized world. Results provide insight into the biological effects of nickel on human CD3+ T cells. We obtained mRNA of pur...
ORGANISM(S): Homo sapiens 
2011-05-18 | E-GEOD-23387 | biostudies-arrayexpress
TranscriptomicsGene expression data from the LEC rat model with naturally occuring and oxidative stress induced liver tumorigenesis
To elucidate the fundamental molecular mechanisms responsible for multistep hepatotumorigenesis, this study investigated genes that were upregulated in a stepwise manner from the naïve liver condition through to chronic oxidative stress-induced hepatitis and liver tumor by time-series microarray ana...
ORGANISM(S): Rattus norvegicus 
2009-07-30 | E-GEOD-17384 | biostudies-arrayexpress
UnknownCharacterization of clinical and genetic risk factors associated with dyslipidemia after kidney transplantation.
Not available
S-EPMC4402561 | biostudies-literature
TranscriptomicsGene expression profiles in liver of F344 rat treated with chemical
The rodent carcinogenicity test requires extremely long test term and large examination cost. Therefore, now we need to develop a short term and low cost screening method. We already developed a chemical carcinogenicity short term screening method CARCINOscreenM-BM-.. This study was performed to va...
ORGANISM(S): Rattus norvegicus 
2013-04-02 | E-GEOD-45650 | biostudies-arrayexpress
TranscriptomicsGene expression profiles in liver of Sprague-Dawley rat using two types of anesthesia.
To reveal influence of anesthesia in toxicogenomics study, gene expression analysis of liver of Sprague-Dawley rat after isoflurane anesthesia or CO2/O2 anesthesia was performed. The liver samples were excised from each rat after isoflurane anesthesia or CO2/O2 anesthesia. The gene expression profil...
ORGANISM(S): Rattus norvegicus 
2015-07-24 | E-GEOD-71277 | biostudies-arrayexpress
MetabolomicsComputational mass spectrometry accelerates C=C position-resolved untargeted lipidomics using oxygen attachment dissociation
Mass spectrometry-based untargeted lipidomics has revealed the lipidome atlas of living organisms at the molecular species level. Despite the double bond (C=C) position being a crucial factor for enzyme preference, cellular membrane milieu, and biological activity, the C=C defined structures have no...
2022-11-09 | MTBLS5861 | MetaboLights
TranscriptomicsInterleukin-4 and interleukin-13 cytokines effect on epidermal keratinocytes
Analysis of cultured epidermal keratinocytes treated with interleukin-4 (IL-4) and interleukin-13 (IL-13). IL-4 and IL-13 are up-regulated in atopic dermatitis. Results provide insight into the role of IL-4 and IL-13 cytokines in the pathogenesis of atopic dermatitis. Analysis of epidermal keratino...
ORGANISM(S): Homo sapiens 
2010-10-31 | E-GEOD-20706 | biostudies-arrayexpress
TranscriptomicsRat liver. Control vs. Chemical treated, 3 days
The final goal of this study is to develop a short term and highly accurate prediction method of carcinogenicity based on gene expression profile of rats administrated by carcinogens. We conducted 3 days-, 14 days- and 28 days-repeated dose experiments in male F344 rats with 47 carcinogens and 26 no...
ORGANISM(S): Rattus norvegicus 
2009-06-22 | E-GEOD-16340 | biostudies-arrayexpress
TranscriptomicsRat liver. Control vs. Chemical treated, 28 days
The final goal of this study is to develop a short term and highly accurate prediction method of carcinogenicity based on gene expression profile of rats administrated by carcinogens. We conducted 3 days-, 14 days- and 28 days-repeated dose experiments in male F344 rats with 47 carcinogens and 26 no...
ORGANISM(S): Rattus norvegicus 
2010-05-19 | E-GEOD-16394 | biostudies-arrayexpress
ProteomicsProteomic analysis of cochlear perilymph in a mouse model of Alzheimer's disease
This study referred to the changes in protein abundance of App(NL-GF/NL-GF) and App(wt/wt) mice perilymph. Liquid chromatography-tandem mass spectrometry with MS2-based quantification of tandem mass tag was utilized.
ORGANISM(S): Mus Musculus (mouse) 
2024-04-15 | PXD046317 | JPOST Repository
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