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TranscriptomicsCloning of 50-75 nt small RNAs associated with Armitage in OSCs
Armitage (Armi) is a component of Yb bodies and functions in the primary piRNA processing pathway. Armi interaction with Piwi does not require Yb expression; however, without Yb, the Armi-Piwi complex does not localize at Yb bodies and contains few piR-ILs (small RNAs associated with Armitage compl...
ORGANISM(S): Drosophila melanogaster 
2010-10-24 | E-GEOD-23931 | biostudies-arrayexpress
ProteomicsAnalysis of Mettl1 interacting proteins in Drosophila
Mass spec analysis was performed to identify interacting proteins with FLAG-tagged Mettl1 in Drosophila ovary.
ORGANISM(S): Drosophila Melanogaster (fruit Fly) 
2024-08-20 | PXD044501 | JPOST Repository
TranscriptomicsPiwi modulates chromatin accessibility by regulating multiple factors including histone H1 to repress transposons
PIWI-interacting RNAs (piRNAs) mediate transposable element (TE) silencing at the transcriptional or post-transcriptional level in animal gonads. In the Drosophila ovary, Piwiâ??piRNA complexes (Piwiâ??piRISCs) repress TE transcription by modifying the chromatin state, such as H3K9me3 marks. Here, w...
ORGANISM(S): Drosophila melanogaster 
2016-06-30 | E-GEOD-81434 | biostudies-arrayexpress
TranscriptomicsFLX sequencing of Piwi-associated small RNAs extracted from Drosophila ovarian somatic cells (OSC)
piRNAs function in silencing retrotransposons by associating with the PIWI proteins, AGO3, Aub, and Piwi, in Drosophila germlines. Bioinformatics analyses of piRNAs in Drosophila ovaries suggested that piRNAs are produced by two systems, the primary processing pathway and the amplification loop, fro...
ORGANISM(S): Drosophila melanogaster 
2009-10-01 | E-GEOD-15137 | biostudies-arrayexpress
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