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ProteomicsInhibition of T cell activation and function by the CIN85 adaptor protein
CIN85 is ubiquitously expressed adaptor protein. In T cells, CIN85 is recruited to the TCR signaling complex and inhibit TCR signaling. To reveal the molecular function of CIN85-mediated inhibition, we performed Flag-CIN85 (CIN85dA) immuno-precipitation and identified the binding proteins. As a nega...
ORGANISM(S): Mus Musculus (mouse) 
2019-01-16 | PXD012369 | JPOST Repository
ProteomicsTMPRSS2-induced Golgi disruption restricts the incorporation of virus envelope glycoproteins into virions
Understanding the relationship between viral proteins and host factors is essential for developing strategies to control virus infections. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infects host cells using angiotensin converting enzyme 2 (ACE2) and transmembrane protease, serine 2...
ORGANISM(S): Homo Sapiens (human) 
2026-04-15 | PXD065094 | JPOST Repository
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