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TranscriptomicsIdentification of MicroRNA Expression Patterns and a MicroRNAs/mRNA Regulatory Network in Multiple Myeloma
To date, little evidence of miRNA expression/deregulation in multiple myeloma (MM) has been reported. To characterize miRNA expression profiling of MM plasma cells (PCs) and integrate miRNA expression data with other molecular features of MM patients, global miRNA expression profiles were generated ...
ORGANISM(S): Homo sapiens 
2010-06-21 | E-GEOD-17498 | biostudies-arrayexpress
GenomicsCo-regulation of transcription factor binding and nucleosome occupancy through DNA features of mammalian enhancers
In mammalian cells transcription factors (TFs) preferentially bind sites contained in regions of high nucleosomal occupancy, as determined by nucleotide-dependent computational analysis. This observation suggests that nucleosomes may act as gatekeepers of TF binding sites. We hypothesized that in ma...
ORGANISM(S): Mus musculus 
2014-05-08 | E-GEOD-50762 | biostudies-arrayexpress
ProteomicsCD300e modulates metabolic programs in adipose tissue macrophages during obesity
Previous studies in monozygotic twins discordant for body mass index (BMI) revealed that obese individuals exhibit elevated expression of the immune receptor CD300e in white adipose tissue (WAT). Notably, CD300e levels decreased following weight loss, implicating its involvement in adipose tissue re...
ORGANISM(S): Mus musculus (Mouse) 
2026-09-14 | PXD072156 | Pride
TranscriptomicsTranscription factor transcriptome during somatic embryogenesis (SE) in Arabidopsis thaliana
To identify transcription factor (TF) genes exhibiting preferential expression during SE, expression profiles of 1,880 TFs were compared in two genotypes with largely different capacities for SE induction in IZE culture on auxin medium, namely the highly embryonic Col-0 accession and the tanmei muta...
ORGANISM(S): Arabidopsis thaliana 
2013-07-31 | E-GEOD-45697 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Arabidopsis seedlings to chito-tetramers, chito-octamers and hydrolized chitin
Using the ATH1 Affymetrix microarrays consisting of about 23,000 genes, we examined the response of Arabidopsis seedlings to chito-tetramers, chito-octamers and hydrolyzed chitin after 30 min of treatment.
ORGANISM(S): Arabidopsis thaliana 
2007-07-12 | E-GEOD-2538 | biostudies-arrayexpress
TranscriptomicsRNA-Seq of in vitro thyroid mouse organoids exposed to a dose range of phthalates for 24 hours. ATAC-Seq of human epithelial thryoid cell line Nthy-ori 3-1 exposed to DEHP or DINP (1 uM) for 5 days
Mouse RNA-Seq: cells derived from recombinant embryonic stem cell line (A2LoxNkx2-1-Pax8) were used. Mouse embryonic stem cell-derived thyroid follicles were exposed to a dose range of phthalates (DEHP, DIDP, DINP at 1-10-100 nM-1-10 uM; DnOP at 2-20-200 nM-2-20 uM) for 24 hours. Every condition was...
ORGANISM(S): Mus musculus 
2023-09-03 | E-MTAB-12830 | biostudies-arrayexpress
GenomicsGenomic binding of Pol III transcription machinery and relationship with TFIIS distribution in mouse embryonic stem cells
RNA polymerase (RNA Pol) III synthesizes the tRNAs, the 5S ribosomal RNA and a small number of untranslated RNAs. In vitro, it also transcribes short interspersed nuclear elements (SINEs). We investigated the distribution of RNA Pol III and its associated transcription factors on the genome of mouse...
ORGANISM(S): Mus musculus 
2011-09-16 | E-MTAB-767 | biostudies-arrayexpress
TranscriptomicsArabidopsis response to four days of limited light treatment -
Experiment was designed to assess the transcriptomic response of wild type Arabidopsis plants (Ler) to 4 days of low light conditions.
ORGANISM(S): Arabidopsis thaliana 
2015-07-29 | E-MTAB-2803 | biostudies-arrayexpress
GenomicsBisulfite sequencing of wild type Arabidopsis plants and H1 mutants
Experiment was performed to assess the effect of H1 histones knock-out on DNA methylation under control conditions and a role of H1.3 in maintaining stress-induced menthylation response.
ORGANISM(S): Arabidopsis thaliana 
2015-01-21 | E-MTAB-2807 | biostudies-arrayexpress
UnknownA Comprehensive Molecular and Serological Investigation of Hepatitis A Virus Among Patients With Suspected Acute Hepatitis: A Brazilian Study.
Not available
S-EPMC12175488 | biostudies-literature
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