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UnknownChoice of CTO scores to predict procedural success in clinical practice. A comparison of 4 different CTO PCI scores in a comprehensive national registry including expert and learning CTO operators.

Background

We aimed to compare the performance of the recent CASTLE score to J-CTO, CL and PROGRESS CTO scores in a comprehensive database of percutaneous coronary intervention of chronic total occlusion procedures.

Methods

Scores were calculated using raw data from 1,342 chronic tota...
S-EPMC8018648 | biostudies-literature
UnknownMechanical power is not associated with mortality in COVID-19 mechanically ventilated patients.

Background

The relative contribution of the different components of mechanical power to mortality is a subject of debate and has not been studied in COVID-19. The aim of this study is to evaluate both the total and the relative impact of each of the components of mechanical power on mortalit...
S-EPMC11861844 | biostudies-literature
UnknownExploring the Mechanisms Underlying Cellular Uptake and Activation of Dendritic Cells by the GK-1 Peptide.
The use of peptides for cancer immunotherapy is a promising and emerging approach that is being intensively explored worldwide. One such peptide, GK-1, has been shown to delay the growth of triple-negative breast tumors in mice, reduce their metastatic capacity, and reverse the intratumor immunosupp...
S-EPMC11656211 | biostudies-literature
UnknownToxicity in Goats Exposed to Arsenic in the Region Lagunera, Northern Mexico.
The Region Lagunera, a region in northeast Mexico, is undergoing significant problems with the quality of its groundwater, which exceeds the permissible limits of contaminants and/or heavy metals stipulated in Mexican legislation. The present study evaluated chronic toxicity in male goats exposed to...
S-EPMC7357139 | biostudies-literature
UnknownAssociation between the CTLA4 +49A/G (rs231775) and CT60 (rs3087243) gene variants with vitiligo: study on a Mexican population.

Background

Vitiligo is characterized by an autoimmune response targeting melanocytes, thus resulting in skin depigmentation. There are several genetic components involved in the development of vitiligo, of which various gene polymorphisms are currently considered as risk factors. For example...
S-EPMC9583029 | biostudies-literature
UnknownEarly Diagnosis of Huntington Disease: Insights from Magnetic Resonance Spectroscopy-A Systematic Review.
Background/Objectives: Huntington's disease (HD) is a fully penetrant neurodegenerative disease with a profound effect on quality of life. In recent years, there has been rapid growth in the description of its pathogenesis and diagnosis. Magnetic resonance spectroscopy (MRS) measurements can ...
S-EPMC11546511 | biostudies-literature
UnknownThe rs11684747 and rs55790676 SNPs of ADAM17 influence tuberculosis susceptibility and plasma levels of TNF, TNFR1, and TNFR2.

Introduction

The proteolytic activity of A Disintegrin and Metalloproteinase 17 (ADAM17) regulates the release of tumor necrosis factor (TNF) and TNF receptors (TNFRs) from cell surfaces. These molecules play important roles in tuberculosis (TB) shaping innate immune reactions and granuloma ...
S-EPMC11177089 | biostudies-literature
UnknownDifferences between surviving and non-surviving venous thromboembolism COVID-19 patients: a systematic review.
BACKGROUND:To our knowledge, the treatment, outcome, clinical presentation, risk stratification of patients with venous thromboembolism and COVID-19 have not been well characterized. METHODS:We searched for systematic reviews, cohorts, case series, case reports, editor letters, and venous thromboemb...
S-EPMC8672331 | biostudies-literature
UnknownVCISpain: protocol for a prospective multicenter observational study to validate a standardized classification tool for tracheal intubation using videolaryngoscopy.

Background and objective

Videolaryngoscopy have transformed airway management by improving intubation success rates compared to direct laryngoscopy. However, its widespread adoption has been hindered by the lack of standardized classification tools for documentation and communication. This m...
S-EPMC12275188 | biostudies-literature
UnknownDevelopment of plastic-degrading microbial consortia by induced selection in microcosms.
The increase in the production of highly recalcitrant plastic materials, and their accumulation in ecosystems, generates the need to investigate new sustainable strategies to reduce this type of pollution. Based on recent works, the use of microbial consortia could contribute to improving plastic bi...
S-EPMC10126402 | biostudies-literature
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