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UnknownDose-adjusted EPOCH-rituximab combined with fludarabine provides an effective bridge to reduced-intensity allogeneic hematopoietic stem-cell transplantation in patients with lymphoid malignancies.
Not available
S-EPMC3295571 | biostudies-literature
TranscriptomicsTranscription profiling of human alveolar macrophages in response to P. aeruginosa and B. cepacia infections
To determine if differences in the severity of pulmonary infection in cystic fibrosis been seen in late isolates od Pseudomonas aeruginosa and Burkholderia cepacia are associated with differences in the initial repsonse of alveolar macrophages (AM) to these pathogens, we assessed gene expression cha...
ORGANISM(S): Homo sapiens 
2008-10-21 | E-GEOD-12245 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human airway epithelium, large airways, from phenotypically normal smokers vs non-smokers
Upregulation of Expression of the Ubiquitin Carboxyl Terminal Hydrolase L1 Gene in Human Airway Epithelium of Cigarette Smokers; The microarray data deposited here is from 11 HG-U133A GeneChips, from 5 normal non-smokers and 6 phenotypic normal smokers, large airways. Samples from the small airways ...
ORGANISM(S): Homo sapiens 
2009-04-25 | E-GEOD-5057 | biostudies-arrayexpress
TranscriptomicsComparison of systematic sequencing errors using spike-in standards
While the importance of random sequencing errors decreases at higher DNA or RNA sequencing depths, systematic sequencing errors (SSEs) dominate at high sequencing depths and can be difficult to distinguish from biological variants. These SSEs can cause base quality scores to underestimate the proba...
ORGANISM(S): Homo sapiens 
2012-03-03 | E-GEOD-36217 | biostudies-arrayexpress
TranscriptomicsEpithelial Expression of Toll-like Receptor 5 is Modulated in Healthy Smokers and Smokers with Chronic Obstructive Lung Disease
The toll-like receptors (TLRs) are important components of the respiratory epithelium host innate defense, enabling the airway surface to recognize and respond to a variety of insults in inhaled air. Based on the knowledge that smokers are more susceptible to pulmonary infection and the airway epith...
ORGANISM(S): Homo sapiens 
2012-10-03 | E-GEOD-30063 | biostudies-arrayexpress
TranscriptomicseQTL analysis of many thousands of expressed genes while simultaneously controlling for hidden factors
Motivation: Identification of eQTL, the genetic loci that contribute to heritable variation in gene expression, can be obstructed by factors that produce variation in expression profiles if these factors are unmeasured or hidden from direct analysis. Methods: We have developed a method for Hidden Ex...
ORGANISM(S): Homo sapiens 
2014-01-07 | E-GEOD-40364 | biostudies-arrayexpress
TranscriptomicsModulation of Cystatin A Expression in Human Airway Epithelium Related to Genotype, Smoking COPD and Lung Cancer
Cystatin A (gene: CSTA), is up-regulated in non-small-cell lung cancer (NSCLC) and dysplastic vs normal human bronchial epithelium. In the context that chronic obstructive pulmonary disease (COPD), a small airway epithelium (SAE) disorder, is independently associated with NSCLC (especially squamous ...
ORGANISM(S): Homo sapiens 
2012-06-19 | E-GEOD-22047 | biostudies-arrayexpress
TranscriptomicsSmoking-dependent Reprogramming of Alveolar Macrophage Polarization: Implication for Pathogenesis of COPD
Background: When exposed to specific stimuli, macrophages exhibit distinct activation programs, M1 and M2 polarization, that define macrophage function as inflammatory/immune effectors or anti-inflammatory/tissue remodeling cells, respectively. Due to their position on the lung epithelial surface, a...
ORGANISM(S): Homo sapiens 
2009-08-09 | E-GEOD-13896 | biostudies-arrayexpress
UnknownA minimum information standard for reproducing bench-scale bacterial cell growth and productivity.
Not available
S-EPMC6283831 | biostudies-literature
UnknownTranscript-based redefinition of grouped oligonucleotide probe sets using AceView: high-resolution annotation for microarrays.
Not available
S-EPMC1853115 | biostudies-literature
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