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Salmon pancreas disease, caused by salmonid alphavirus (SAV), is an economically important disease affecting farmed Atlantic salmon (Salmo salar L.) in Europe, with outbreaks reported in Scotland, Norway, and Ireland. A microarray-based study was performed to evaluate the host transcriptomic respons...
ORGANISM(S): Salmo salar 
YAP is the principle effector of the Hippo signaling pathway; a key regulator of tissue homeostasis whose dysregulation is linked to cancer development. YAP regulation of gene expression is thought to involve the TEAD transcription factor family. Here we show that YAP and TEAD1 binding always co-occ...
ORGANISM(S): Homo sapiens 
The current study examines the functional role of VEPH1, a PH domain containing protein and the human ortholog of Drosophila melted, in ovarian cancer cell lines. Elevated VEPH1 is associated with FOXO and Hippo signaling and was found to suppress TGF-ß induced target genes. SKOV3 cell lines were es...
ORGANISM(S): Homo sapiens 
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