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TranscriptomicsCombinatorial role of two paralogous splicing factors, hnRNP L and L-like, in multiple-exon regulation of CD45 alternative splicing
The goal of this study was to investigate the role of hnRNP L-like in alternative pre-mRNA splicing in human B-cells through an RNA-Seq approach. RNA-Seq was performed in DG75 cell line with over expression of hnRNP L-like or GFP as control.
ORGANISM(S): Homo sapiens 
2012-03-28 | E-GEOD-33013 | biostudies-arrayexpress
GenomicsLRH-1 and PTF1-L coregulate an exocrine pancreas-specific transcriptional network for digestive function [ChIP-Seq]
We have determined the cistrome and transcriptome for the nuclear receptor liver receptor homolog-1 (LRH-1) in the exocrine pancreas. Chromatin immunoprecipitation (ChIP)-seq and RNA-seq analyses reveal that LRH-1 directly induces expression of genes encoding digestive enzymes and secretory and mit...
ORGANISM(S): Mus musculus 
2011-12-09 | E-GEOD-34295 | biostudies-arrayexpress
UnknownBiosynthesis of Oxetanocin-A Includes a B12-Dependent Radical SAM Enzyme That Can Catalyze both Oxidative Ring Contraction and the Demethylation of SAM.
Not available
S-EPMC7904626 | biostudies-literature
UnknownNMR structure of a heterodimeric SAM:SAM complex: characterization and manipulation of EphA2 binding reveal new cellular functions of SHIP2.
Not available
S-EPMC3516615 | biostudies-literature
UnknownStructure-guided discovery of the metabolite carboxy-SAM that modulates tRNA function.
Not available
S-EPMC3895326 | biostudies-literature
TranscriptomicsTranscription profiling of S. cerevisiae wild type versus delta vts1
The experiment was designed to look for genes up/downregulated in the absense of Vts1p compared to wild-type cells grown in steady state conditions. Experiment Overall Design: 3 chips delta VTS1 vs. 2 wild type control chips
ORGANISM(S): Saccharomyces cerevisiae 
2008-06-12 | E-GEOD-3859 | biostudies-arrayexpress
TranscriptomicsLRH-1 and PTF1-L coregulate an exocrine pancreas-specific transcriptional network for digestive function [RNA-Seq]
Two separate pools of three Flox or two Lrh1t-/- pancreas RNA preparations was subjected to the Illumina RNA-seq protocol. Examination of mRNA levels in induced Lrh1 pancreas knockout and wild-type mice.
ORGANISM(S): Mus musculus 
2011-11-30 | E-GEOD-34030 | biostudies-arrayexpress
UnknownRadical SAM-dependent formation of a nitrogenase cofactor core on NifB.
Not available
S-EPMC9526504 | biostudies-literature
TranscriptomicsGenome-Wide Yan Chromatin Occupancy in Drosophila Embryos
The ETS transcriptional repressor Yan functions as part of a developmental switch that in response to receptor tyrosine kinase signaling, transitions from a high-Yan to a low-Yan state to direct specification of a variety of cell fates. To date very few direct target genes have been identified, nor ...
ORGANISM(S): Drosophila melanogaster 
2013-03-01 | E-GEOD-34038 | biostudies-arrayexpress
UnknownEPR Characterization of the BlsE Substrate Radical Offers Insight into the Determinants of Reaction Outcome that Distinguish Radical SAM Dioldehydratases from Dehydrogenases.
Not available
S-EPMC11826333 | biostudies-literature
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