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ProteomicsA safe alternative to H37Rv: the attenuated double auxotroph Mycobacterium tuberculosis ΔleuDΔpanCD
Currently available model organisms such as Mycobacterium smegmatis and Mycobacterium bovis Bacillus Calmette-Guérin (BCG) have significantly contributed to our understanding of tuberculosis (TB) biology, these models have limitations such as differences in genome size, growth rates and virulence. A...
ORGANISM(S): Mycobacterium tuberculosis 
2019-07-30 | PXD013677 | Pride
Biosafety level 2 Model organism Mycobacterium tuberculosis Attenuated auxotroph 
ProteomicsPulse-chase SILAC of Mycobacterium tuberculosis infected THP-1 macrophages
Pulse chase SILAC was used to identify protein turnover within human macrophages infected with mycobacterium tuberculosis CDC1551, a ppe38-71 mutant strain, a complemented strain and an uninfected control.
ORGANISM(S): Homo sapiens (Human) 
2021-06-15 | PXD021166 | Pride
Lc-ms/ms Tuberculosis Silac Macrophages 
ProteomicsGeLC-MS/MS of H37Rv and two clinical isolates of Mycobacterium tuberculosis
Clinical isolates were made available from an extensive longitudinal collection of M. tuberculosis isolates circulating in the Western Cape of South Africa. Clinical isolates SAWC3651 and SAWC3517, belonging to the LAM (lineage 4.3) genotype and IS6110 family 14 and 9, respectively, and M. tubercul...
ORGANISM(S): Mycobacterium Tuberculosis (ncbitaxon:1773) 
2017-06-30 | MSV000081205 | MassIVE
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